Vol. 11 | No. 3 |1328 - 1333 | July - September | 2018
ISSN: 0974-1496 | e-ISSN: 0976-0083 | CODEN: RJCABP
http://www.rasayanjournal.com
http://www.rasayanjournal.co.in
Rasayan J. Chem., 11(3), 1328-1333(2018)
http://dx.doi.org/10.31788/RJC.2018.1133095
KINETIC-SPECTROPHOTOMETRICDETERMINATION OF p-
BROMOANILINEAT THE MICROGRAM LEVEL
Kavita Rawat, Jaspal Singh*, R. D. Kaushik and Nishant Khandelwal
Department of Chemistry, GurukulaKangriVishwavidyalayaHaridwar,
*E-mail : sjs2874@yahoo.com
ABSTRACT
The determination of p-Bromoaniline(PBA) was investigated by kinetic-spectrophotometric method followed by the
progress of Mn
II
catalyzed reduction of periodate ion in the acetone-water medium. The reaction was found to be
first order with respect to the catalyst, substrate,and oxidant each. The reaction was followed by monitoring the
increase in the absorbance of the reaction intermediate. The main reaction product characterized on the basis of
melting point and spectroscopic studies is 4-methyl-1,2-benzoquinone. The effect of pH, dielectric constant of
medium and free radical scavengers were studied to develop the best-fit conditions for developing a new and simple
kinetic-spectrophotometric method for microgram determination of p-Bromoanilinein the range 0.52µ g/cm
3
to
48.37 µ g/cm
3
.The characteristics of various calibration curves, detection limits, percentage recovery,and effect of
interferants, correlation coefficient and comparison of the proposed methods with other reported methods are
presented in this article.
Keywords: Microgram Estimation,periodate ion, Mn
II
catalyzed,p-Bromoaniline, 4-Bromo-1,2-Benzoquinone.
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INTRODUCTION
Aromatic amines are highly polar organic compounds that are widely used as intermediates or produced
in various fields such as drugs, dyes, tobacco smoke, pesticides and pharmaceutical industries and as
antioxidants in the polymer industries.
1,2
Aromatic amines are suspected to be carcinogenic and highly
toxic to the human body, aquatic organisms and environment, therefore de-contamination of aromatic
amines from industrial wastewater is necessary. In order to understand the behavior of aromatic amines
and fate in human body and environment, highly sensitive and selective methods for the determination of
aromatic amines is necessary.
Many workers have reported the estimation of some aromatic amines in smaller amounts in different
media and using various complex reaction systems involving complicated pre-treatment and employing
various techniques like NMR, IR Spectroscopy, Spectrophotometry, Polarography, Flow injection
analysis, Solvent extraction, Raman spectroscopy, and various chromatographic techniques including
TLC, gas chromatography, HPLC, reversed phase HPLC, GC-MS, GC/LC, GC-ECD, ion exchange
chromatography and electrochemical detection.
3-12
The only report available in the literature regarding the
kinetic-spectrophotometric estimation of some anilines is based on their oxidation by periodate ion in
aqueous/ mixed media.
13-14
Earlier reports have proposed that Periodate oxidation of aromatic amines has
not been explored widely for kinetic spectrophotometric determination of amines and only a few attempts
have been made in this direction.
15-24
Some reports are available on Evaluation of stability constant of
ternary intermediate complex formation in Mn
II
catalyzed periodate oxidation of 2,5-xylidine by stopped
flow method.
31
Some aniline was investigated as fabrication of polyaniline nanofiber modified carbon
paste electrodes (GOx/MCPE)
32
.
The detailed kinetic-mechanistic studies on Mn
II
catalyzedthe reduction of periodate by p-
Bromoanilinehas also been reported.
25
This reaction has not been explored for estimation of p-
Bromoaniline(PBA). Present paper deals with a new and simple kinetic-spectrophotometric method