Accepted Manuscript Title: Enhancement of 8-methoxypsoralen topical delivery via nanosized niosomal vesicles: Formulation development, in vitro and in vivo evaluation of skin deposition Author: Ahmed Alaa Kassem Sameh Hosam Abd El-Alim Marwa Hasanein Asfour PII: S0378-5173(16)31149-8 DOI: http://dx.doi.org/doi:10.1016/j.ijpharm.2016.12.018 Reference: IJP 16289 To appear in: International Journal of Pharmaceutics Received date: 16-10-2016 Revised date: 6-12-2016 Accepted date: 8-12-2016 Please cite this article as: Kassem, Ahmed Alaa, El-Alim, Sameh Hosam Abd, Asfour, Marwa Hasanein, Enhancement of 8-methoxypsoralen topical delivery via nanosized niosomal vesicles: Formulation development, in vitro and in vivo evaluation of skin deposition.International Journal of Pharmaceutics http://dx.doi.org/10.1016/j.ijpharm.2016.12.018 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.