Available online at www.sciencedirect.com ScienceDirect Materials Today: Proceedings 5 (2018) 16258–16266 www.materialstoday.com/proceedings 2214-7853© 2017 Elsevier Ltd. All rights reserved. Selection and/or Peer-review under responsibility of International Conference on Advanced Materials(SCICON ‘16). SCICON 2016 Comparative evaluation of efficacy of Zinc oxide and Copper oxide nanoparticles as antimicrobial additives in alginate impression materials Kishore Ginjupalli a *, Ramakrishna Alla b , Tushar Shaw c , Chaitanya Tellapragada c , Lokendra Kumar Gupta d , Nagaraja Upadhya P a a Department of Dental Materials, Manipal College of Dental Sciences, MAHE, Manipal – 576104, India b Department of Dental Materials, Vishnu Dental College, Bhimavaram, Andhra Pradesh, India c Department of Microbiology, Kasturba Medical College, MAHE, Manipal – 576104, India d Department of Prosthodontics and Crown & Bridge, Manipal College of Dental Sciences, MAHE, Manipal - 576104, India Abstract Two commercially available alginate impression materials were incorporated with varying concentrations of zinc oxide nanoparticles (ZnO-NP) or copper oxide nanoparticles (CuO-NP) and their properties such as antimicrobial activity, gel strength, permanent deformation, gelation time and flow were measured. The results showed that alginates incorporated with nanoparticles exhibited concentration dependent antimicrobial activity. It was also observed that incorporation of nanoparticles did not adversely affect the clinically important properties of alginates. From these results, it can be concluded that incorporation nanoparticles to alginate materials can be considered for effective disinfection without significantly affecting their properties. © 2017 Elsevier Ltd. All rights reserved. Selection and/or Peer-review under responsibility of International Conference on Advanced Materials (SCICON ‘16). Keywords: Alginate; Antimicrobial activity; Disinfection; Irreversible Hydrocolloids; Nanoparticles; Zinc Oxide; Copper Oxide. * Corresponding author. Tel.: +919448251849. E-mail address:kishore.gp@manipal.edu