Accepted Manuscript Title: In vitro 4-Aryloxy-7-chloroquinoline derivatives are effective in mono- and combined therapy against Leishmania donovani and induce mitocondrial membrane potential disruption Authors: Elizabeth Valdivieso, Fabiola Mej´ ıas, Carlos Torrealba, Gustavo Benaim, Vladimir V. Kouznetsov, Felipe Sojo, Fernando A. Rojas-Ruiz, Francisco Arvelo, Francehuli Dagger PII: S0001-706X(18)30016-0 DOI: https://doi.org/10.1016/j.actatropica.2018.03.023 Reference: ACTROP 4624 To appear in: Acta Tropica Received date: 9-1-2018 Revised date: 27-2-2018 Accepted date: 24-3-2018 Please cite this article as: Valdivieso, Elizabeth, Mej´ ıas, Fabiola, Torrealba, Carlos, Benaim, Gustavo, Kouznetsov, Vladimir V., Sojo, Felipe, Rojas-Ruiz, Fernando A., Arvelo, Francisco, Dagger, Francehuli, In vitro 4-Aryloxy-7-chloroquinoline derivatives are effective in mono- and combined therapy against Leishmania donovani and induce mitocondrial membrane potential disruption.Acta Tropica https://doi.org/10.1016/j.actatropica.2018.03.023 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.