Final revision date: 25/08/04 Journal of Neuroendocrinology Title: ‘Central and peripheral administration of kisspeptin-10 stimulates the hypothalamic-pituitary-gonadal axis’ E.L. Thompson*, M. Patterson*, K.G. Murphy, K.L. Smith, W.S. Dhillo, J. F. Todd, M.A. Ghatei and S.R. Bloom. Department of Metabolic Medicine, Imperial College Faculty of Medicine, Hammersmith Campus, Du Cane Road, London W12 ONN, UK. * These authors contributed equally to these studies Key Words: metastin, kisspeptin, GPR54, luteinizing hormone releasing hormone, gonadotropins. Address for correspondence: Professor S.R. Bloom, Department of Metabolic Medicine, Imperial College Faculty of Medicine, Hammersmith Campus, Du Cane Road, London W12 ONN, UK. Phone +44-20-8383 3242 Fax +44-20-8383-3142 E-mail: s.bloom@imperial.ac.uk Running Title: Kisspeptin stimulates the HPG axis 1