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Introduction
Currently obesity is a pandemic begins in early childhood and
becomes more prevalent in adulthood, consequently resulting in
increased risk of metabolic diseases and increased cardiovascular
morbidity and mortality.
1
2014 the World Health Organization (WHO) reported that 39%
of those over 18 years in the world were overweight and 13% were
obese.
2
In Peru, according Demographic and Health Survey (DHS
2014), in patients over 15 years of age, the prevalence of overweight
and obesity 34.7% 17.5% reported. These alterations of overweight
and obesity are higher in Lima (40.2%) and urban (21.3%) compared
to rural areas (6.6%).
3
WHO defnes obesity as abnormal or excessive fat accumulation
that can be harmful to health, since the 80s, the use of BMI (Body
Mass Index) was introduced to defne overweight (BMI≥25 kg/m
2
)
and obesity (IMC≥ 30kg/m
2
). Also it determined to be important to
consider two subtypes of obesity: the central, visceral or android
obesity (waist circumference in men and women≥90cm≥80cm for
people of Central and South America) and peripheral gynoid obesity
or (abdominal girth in men<90 cm and in women<80 cm).
4
From
this defnition, studies have been showing that the amount of visceral
adipose tissue is directly correlated with abnormal metabolic profle
and increased cardiovascular risk.
The components of central obesity and metabolic alterations are
part of the so-called Metabolic Syndrome (MS), 2005 the International
Diabetes Federation (IDF), proposed as a prerequisite for this
syndrome increased abdominal girth (values according to ethnicity)
to which you add one or more of the following criteria: increased
triglycerides with low HDL, hypertension, associated with insulin
resistance and/or reduced glucose metabolism, thus giving the great
importance of central obesity risk of metabolic and cardiovascular
diseases.
5
Since 2000 the concept of “Waist hypertriglyceridemic” is
released as a single phenotype to detect patients with cardiometabolic
risk; hypertriglyceridemia (≥177mg/dl) and the increase in
abdominal circumference (males ≥90cm) is associated with a
metabolic triad unconventional risk variables as hyperinsulinemia,
hiperapolipoproteína B and small, dense LDL. This atherogenic
metabolic triad is associated with an increase of over 20 times of
risk of ischemic heart disease in middle-aged men - Cardiovascular
Quebec study - beyond the presence of traditional risk factors.
6
For this increasing prevalence of obesity in our country and the
world, must be sought an affordable cost and simple clinical tool to
identify cardiometabolic risk for developing cardiovascular disease
and type 2 diabetes mellitus in our population, ideally this identifcation
must be made from the frst level of care. Hypertriglyceridemic
waist phenotype is described in many populations as an ideal and
inexpensive tool to identify those patients at risk; in Peru there are
few studies regarding the phenotype hypertriglyceridemic waist.
The aim of this work is to determine the clinical - laboratorial
hypertriglyceridemic waist phenotype in military personnel, it is
important for early detection of patients at risk for cardio metabolic
diseases.
Materials and methods
Observational, descriptive, retrospective cross-sectional
study. No experimental. Medical records of patients treated at the
Endocrinology Service of Military Hospital between January 2016
and March 2017. Patients were reviewed over 18 years, with the
presence of hypertriglyceridemia, elevated waist circumference
are included according to sex and have clinical and laboratory data
complete; pregnant patients were excluded, diagnosed Diabetes
Mellitus, decompensated and lipid-lowering therapy at the time of the
frst evaluation Hypothyroidism. The research included the variables
age, sex, weight, height, BMI, waist circumference, blood pressure,
presence of acanthosis, basal glycemia, basal insulin, HOMA IR
calculation, cholesterol and fractions and TGP,
The data are presented using descriptive statistics, software used
in Statistical Package for Social Sciences (SPSS) version 24. The
Endocrinol Metab Int J. 2019;7(4):86‒89. 86
© 2019 Navarrete-Mejía et al. This is an open access article distributed under the terms of the Creative Commons Attribution License,
which permits unrestricted use, distribution, and build upon your work non-commercially.
Phenotype hypertriglyceridemic waist in personal
and military family, 2016-2017. Lima - Peru
Volume 7 Issue 4 - 2019
Pedro J Navarrete-Mejía,
1
Cecilia Núñez-
Calderón
2
1
Public Health Research Center, Investigation Institute, Faculty
of Human Medicine, University of San Martín de Porres, Peru
2
Medical endocrinologist, Master of Medicine with mention in
Endocrinology, Central Military Hospital, Lima Peru
Correspondence: Pedro J Navarrete-Mejía, Public Health
Research Center, Investigation Institute. Faculty of Human
Medicine, Doctor in Public Health, University of San Martín de
Porres, Peru, Tel 3(511)365-2300, (511)365-3640, Fax 365-0485,
Email
Received: June 13, 2019 | Published: July 03, 2019
Abstract
Objective: To know the clinical and laboratory Characteristics of the hypertriglyceridemic
waist phenotype in the Patients of a military hospital, 2016-2017.
Material and methods: Observational, descriptive, retrospective cross-sectional study.
Non-experimental design. We reviewed the Clinical Histories of Patients Treated in the
endocrinology service of a Military Hospital, from January 2016 to March 2017; 82
Patients With complete clinical and laboratory data were included in the medical records.
Results: Mean age 55.4 years (range 22-78 years), higher frequency in evils (59.8%),
presence of overweight (46.34%), some degree of obesity (50%), acanthosis nigricans
presence of (40.2%) (58.5%), HOMA-IR was 70.7% in ≥2.77, high Total cholesterol (61%)
and low HDL (62.2%), high TGP (34.1%).
Conclusions: The hypertriglyceridemic waist phenotype is a good marker of multiple
metabolic Alterations, Strengthening STI use for early detection of cardiometabolic risk
overall.
Keywords: Insulin resistance, hypertriglyceridemia, acanthosis
Endocrinology & Metabolism International Journal
Review Article
Open Access