Amrit Godbole et al., Int. J. Res. Pharm. Sci., 2021, 12(2), 1572-1578 RĊěĎĊĜ AėęĎĈđĊ IēęĊėēĆęĎĔēĆđ JĔĚėēĆđ Ĕċ RĊĘĊĆėĈč Ďē PčĆėĒĆĈĊĚęĎĈĆđ SĈĎĊēĈĊĘ Published by JK Welfare & Pharmascope Foundation Journal Home Page: www.pharmascope.org/ijrps Role of Sneha kalpana (Oil based formulation) in the management of Vataja Prameha (Vata predominance Prameha) w.s.r. to Khadira-kramuka kashaya siddha taila Amrit Godbole *1 , Abhinav 1 , Sweta K M 2 , Arpit Srivas 3 , Vandana Singh 1 , Pratyush Sharma 1 , Singh O P 1 , Tripathi J S 1 1 Faculty of Ayurveda, Institute of Medical Sciences, BHU, Varanasi-221005, Uttar Pradesh, India 2 Dr Vijay Ayurvedic College, Kaithi, Varanasi, Uttar Pradesh, India 3 UP State Government, Uttar Pradesh, India Article History: Received on: 20 Feb 2021 Revised on: 24 Mar 2021 Accepted on: 25 Mar 2021 Keywords: Diabetes Mellitus, Metabolic Syndrome, Obesity, Prameha, Khadira- Kramukakashaya Siddha Tail AćĘęėĆĈę Diabetes mellitus is a fast-growing pandemic. In India, the urban population is more prone to disease rather than the rural Indian population. Dietary habits, faulty lifestyle, and urbanization leading to reduced physical exercise may be responsible to a large extent. Indian system of medicine, namely Ayurveda cited a disease entity named Prameha. It is a clinical syndrome that includes various clinical conditions like, obesity, pre-diabetes, diabetes, and metabolic syndrome. The symptomatology, types, and sub-types mentioned in the con- text shows relevance with modern times rationale of free fatty acid and its role in peripheral insulin resistance. The article put an emphasis on those cases of chronic diabetes (DM type 2) which becomes insulin dependent in later phase of life and its coherence with Vatolwana prameha of kaphaja and pittaja vari- ety(Kaphaja and Pittajaprameha with predominant Vata). This review article focuses on the Ayurvedic management of chronic insulin dependent type 2 diabetics. Various research papers indexed in Pubmed, SCOPUS, and Web of Science was deeply studied and cited appropriately in the article. The clos- est possible correlation of modern and Ayurveda principles and their rele- vance in the present time is tried to be drawn. The treatment protocol given in Ayurveda texts is scientiϐic enough to be taken into consideration for making it as the ϐirst-line treatment of not only diabetes mellitus but also in the cases of obesity and metabolic syndrome. * Corresponding Author Name: Amrit Godbole Phone: +91 7408859248 Email: amritgodbole2@gmail.com ISSN: 0975-7538 DOI: https://doi.org/10.26452/ijrps.v12i2.4742 Production and Hosted by Pharmascope.org © 2021 | All rights reserved. INTRODUCTION Prameha as mentioned in ancient Ayurveda texts depicting a disease of Mutravaha sansthana (Uri- nary system) but most importantly it is a dis- ease of metabolism. Urinary tract related symp- toms are frequently associated at every stage of the disease (Puranik and Patwardhan, 2012). The classical symptom representing of Prameha is pas- sage of excess amount of Turbid urine (Prabhuta Avila mutrata) (Tewari et al., 2017). Prameha also derives its name from its character simi- lar to Polyuria (Shrikantha, 2004). The ancient Ayurveda texts scripted Prameha roga (Disease) in a much elaborated manner. Detailed descrip- 1572 © International Journal of Research in Pharmaceutical Sciences