Journal of Sol-Gel Science and Technology (2020) 96:153–165 https://doi.org/10.1007/s10971-020-05384-y ORIGINAL PAPER: NANO-STRUCTURED MATERIALS (PARTICLES, FIBERS, COLLOIDS, COMPOSITES, ETC.) Synthesis and characterization of advanced hybrid titanium compounds/F-MWCNTs nanocomposites and their antibacterial activities Harsh Bajpai 1 ● Medha Mili 1 ● S. A. R. Hashmi 1 ● A. K. Srivastava 1 ● Anita Tilwari 2 ● Mamata Mohapatra 3 ● Sarika Verma 1 Received: 16 April 2020 / Accepted: 30 July 2020 / Published online: 29 August 2020 © Springer Science+Business Media, LLC, part of Springer Nature 2020 Abstract The main objective of this paper is to synthesize advanced hybrid titanium compounds/F-MWCNTs nanocomposites for biomedical applications using a low temperature chemical method followed by an annealing processing. The uniqueness of our approach consists of utilizing the raw materials namely titanium compounds with varying morphological shapes i.e., spherical and nanoflowers nanoparticles for developing advanced nanocomposites A & B having hybrid organic–inorganic titanium compounds namely titanium oxide and sodium titanium oxide, which are conformally impregnated on F-MWCNTs and are useful for biomedical applications. Various techniques such as X-ray Diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), ThermoGravimetric Analysis (TGA), X-ray Photoelectron Spectroscopy (XPS), Atomic Force Microscopy (AFM), Transmission Scanning Electron Microscopy (TEM), and Energy Dispersive X-ray Analysis (EDX), were performed to study and confirm the structures of the developed advanced hybrid titanium compounds F-MWCNTS nanocomposite. The developed nanocomposite A has shown antibacterial potential against test microbes, gram positive, and gram negative bacteria namely Staphylococcus aureus, Escheria coli, Lactobacillus planetarum, Lactobacillus acidophilus, and Enterococcus faecalis using the disc diffusion method at different concentrations. The developed material is useful for various applications like antibacterial agents, sodium insertion material of sodium ion batteries, shielding radiations like UV, X-rays while performing dental radiographic examinations of the patients. Graphical Abstract * Sarika Verma sarika.verma@ampri.res.in 1 Council of Scientific and Industrial Research- Advanced Materials and Processes Research Institute, Hoshangabad Road, Bhopal, MP 462064, India 2 Centre of Excellence in Biotechnology, M.P. Council of Science and Technology, Nehru Nagar, Bhopal, MP 462003, India 3 Council of Scientific and Industrial Research-IIMT, Bhubaneswar, Odisha 751013, India Supplementary information The online version of this article (https:// doi.org/10.1007/s10971-020-05384-y) contains supplementary material, which is available to authorized users. 1234567890();,: 1234567890();,: