Accepted Article This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/iej.12981 This article is protected by copyright. All rights reserved. MR. GUILHERME FERREIRA SILVA (Orcid ID : 0000-0002-3271-541X) PROF. MÁRIO TANOMARU-FILHO (Orcid ID : 0000-0002-2574-4706) PROF. PAULO SÉRGIO CERRI (Orcid ID : 0000-0001-5756-5828) Article type : Original Scientific Article Mast cells and immunoexpression of FGF-1 and Ki-67 in rat subcutaneous tissue following the implantation of Biodentine and MTA Angelus T. Silva da Fonseca 1 , G. F. Silva 2 , J. M. Guerreiro-Tanomaru 1 , E. Sasso-Cerri 3 , M. Tanomaru-Filho 1 , P. S. Cerri 3 1 Department of Restorative Dentistry, Dental School – São Paulo State University (UNESP), Araraquara, 2 Pro-Rectory of Research and Post Graduation, School of Dentistry - Universidade Sagrado Coração (USC), Bauru, 3 Laboratory of Histology and Embryology, Dental School – São Paulo State University (UNESP), Araraquara, SP, Brazil. Running title: Biodentine promotes delay in the collagen formation Keywords: biocompatibility; cell proliferation; collagen; fibroblast growth factor-1; immunohistochemistry; mast cells. Address for all correspondence: Prof. Dr. Paulo Sérgio Cerri Laboratory of Histology and Embryology, Dental School, São Paulo State University (UNESP), Araraquara, SP, Brazil. Tel: +55 16 33016497 Fax: +55 16 33016433 e-mail: pcerri@foar.unesp.br