JPET #214189 1 Title Page Trovafloxacin enhances LPS-stimulated production of TNF by macrophages: role of the DNA damage response Kyle L. Poulsen, Jesus Olivero Verbel, Kevin M. Beggs, Patricia E. Ganey and Robert A. Roth Department of Pharmacology & Toxicology, Center for Integrative Toxicology, Michigan State University, East Lansing, MI 48824-1302 (KLP, KMB, PEG and RAR); Environmental and Computational Chemistry Group, School of Pharmaceutical Sciences, University of Cartagena, Cartagena, Colombia (JO) JPET Fast Forward. Published on May 9, 2014 as DOI:10.1124/jpet.114.214189 Copyright 2014 by the American Society for Pharmacology and Experimental Therapeutics. This article has not been copyedited and formatted. The final version may differ from this version. JPET Fast Forward. Published on May 9, 2014 as DOI: 10.1124/jpet.114.214189 at ASPET Journals on January 22, 2022 jpet.aspetjournals.org Downloaded from