This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record . Please cite this article as doi: 10.1002/adem.202000275. This article is protected by copyright. All rights reserved Superparamagnetic manganese ferrite and strontium bioactive glass nanocomposites: Enhanced biocompatibility and antimicrobial properties for hyperthermia application Authors: Himanshu Tripathi a *, Gaurav Chandra Pandey a , Ashutosh Dubey b , Subham Kumar Shaw c , Nand Kishore Prasad c , S.P. Singh b and Chandana Rath a * Affiliation: a School of Materials Science & Technology, IIT (BHU), Varanasi-221005, India. b Department of Ceramic Engineering, IIT (BHU), Varanasi-221005, India. c Department of Metallurgical Engineering, Indian Institute of Technology (Banaras Hindu University), Varanasi-221005, India. Corresponding Authors: E-mail addresses: himanshutripath@gmail.com (Himanshu Tripathi), chandanarath@yahoo.com (Chandana Rath). Abstract:- In this report, the strontium bioactive glass with ferrite composites are studied for the application of biocompatibility and magnetic hyperthermia. The bioactive glass SrBG (46.1SiO 2 - 21.9CaO-24.4Na 2 O-2.6P 2 O 5 -5SrO) prepared by the melt quench technique at 1400°C and manganese ferrite (MnFe 2 O 4 ) prepared by the modified microwave reflux oven, are mixed together and sintered at 400°C for 6h for making composites. The in-vitro bioactivity of these composites is observed by immersing in simulated body fluid (SBF). The growth of the precipitated hydroxyapatite phase observed after SBF treatment is confirmed by the XRD, FTIR and SEM results. The in-vitro cell viability assessment of these composites with MG-63 cell lines indicates that the composites are biocompatible in nature. Further, these composites show the antibacterial effect on the E.coli and S.Aureus bacteria cells. The room temperature superparamagnetic behavior accompanied by the heating ability in these composites proves their potential role for hyperthermia applications. Keywords: Biocomposites; FTIR; Bioactivity; Superparamagnetism; Hyperthermia Accepted Article