Vitamin D Status in Diabetic Ulcer in The Tropical
Area
Raflis
1
, Yanwirasti
2
, Hendro Sudjono Yuwono
3
, Eva Decroli
4
{raflis_rustam@yahoo.co.id
1
}
Surgery Department of Medical Faculty, Universitas Andalas /Dr. M. Djamil Hospital Padang
Indonesia
1
Department of Anatomic Medical Faculty Universitas Andalas Padang Indonesia
2
Surgery Department of Medical Faculty Padjajaran University/ Dr.Hasan Sadikin Hospital Bandung
Indonesia
3
Internal Medicine Department of Medical Faculty Universitas Andalas/Dr. M. Djamil Hospital
Padang Indonesia
4
Abstract. Type 2 diabetes mellitus (T2DM) is a problem in health because it can cause a
high disability and death worldwide. A metabolic disorder occurs which associated with
pathophysiological changes in many organs in type 2 diabetes. Death is not caused by
diabetes directly, but from its complications. Most complications are diabetic ulcers with
a prevalence of 25%
.
This paper was a cross-sectional study that highlight vitamin D status
associated with diabetic ulcer. The study population was patients with diabetic ulcers who
were treated (outpatient and inpatient) in dr. M. Djamil Padang Hospital and Ibnu Sina
Yarsi Padang Hospital and others that met the inclusion and exclusion criteria. The number
of samples was 36 people through interviews and medical record data. Our result shows
data that vitamin D status was below the normal value in more than 50% of the diabetic
ulcer. The results of the relationship between Vitamin D status and Wagner's classification
of diabetic ulcer patients that there was no significant difference between vitamin D status
p=1,000. Vitamin D status can affect some medical condition. Vitamin D prevents and
improves vascular disease, through improvement of anti-inflammatory and finally, it
makes an endothelial dysfunction that contributes to being a diabetic ulcer.
Keywords: Diabetic Ulcer, Vitamin D , Vitamin D Status.
1 Introduction
Type 2 diabetes mellitus (T2DM) is a problem in health because it can cause a high
disability and death worldwide[1]. The global prevalence of type 2 diabetes in adults over the
age of 18 increases from 4.7% in 1980 to 8.5% in 2014, especially in developing and poor
countries [1]. A metabolic disorder occurs which is associated with pathophysiological changes
in many organs in type 2 diabetes. Death is not caused by diabetes directly, but from its
complications. Most complications are diabetic ulcers with a prevalence of 25% [1],[2].
Diabetic ulcers are preceded by peripheral artery disease (PAD), which is experienced by
20% of patients with DM, with various levels of clinical emergency. The process of diabetic
ulcer begins with a state of chronic hyperglycemia which results in arterial endothelial
dysfunction. Many factors and conditions can affect vascular endothelial inflammation, that
ICOMHER 2018, November 13-14, Padang, West Sumatera, Indonesia
Copyright © 2019 EAI
DOI 10.4108/eai.13-11-2018.2283657