Available online at www.sciencedirect.com ScienceDirect Materials Today: Proceedings 9 (2019) 627–632 www.materialstoday.com/proceedings _________________ * Corresponding author. Tel.:+91-7598473275; Fax:+04652-260704 E-mail address:leslysat@gmail.com 2214-7853© 2018 Elsevier Ltd. All rights reserved. Selection and peer-review under responsibility of the scientific committee of the International Conference on Green Methods for Separation, Purification and Nanomaterial Synthesis, GMSP&NS’18, 24–25th April 2018, Centre for Nano and Material Sciences, Jain University, Bangalore 562112, Karnataka, India. GMSP&NS’18 Annona MuricataInspired Synthesis of CeO 2 Nanoparticles and their Antimicrobial Activity S. Sebastiammal a, , A.Mariappan b , K.Neyvasagam b , A. Lesly Fathima a* a Research Department of Physics, Holy Cross College (Autonomous), Nagercoil-629004(Affiliated to Manonmaniam Sundaranar University, Abishekapatti, Tirunelveli-627012, Tamil Nadu, India) b P.G and Research Department of Physics, The Madura College, Madurai-625011,Tamil Nadu, India. Abstract CeO 2 nanoparticles (NPs) have shown promising results as therapeutic agents in biology and medical sciences. In this study, CeO 2 -NPshave been synthesized through green synthetic approach by applying natural matrices(fruit of Annona muricata) as stabilizing agents in order to prepare biocompatible CeO 2 -NPs, thereby solving the challenges regarding safety, and providing the appropriate properties for their effective use in biomedical field.The synthesized CeO 2 nanoparticles are characterized by XRD, FTIR, UV-DRS, FESEM, EDAX, PL and antimicrobial analysis. UV-DRS analysis shows that formation of CeO 2 nanoparticles with maximum absorption at 318 nm.The antibacterial activities of synthesized CeO 2 NPs were carried out against the human pathogenic microorganism by agar-well diffusion method. © 2018 Elsevier Ltd. All rights reserved. Selection and peer-review under responsibility of the scientific committee of the International Conference on Green Methods for Separation, Purification and Nanomaterial Synthesis, GMSP&NS’18, 24–25th April 2018, Centre for Nano and Material Sciences, Jain University, Bangalore 562112, Karnataka, India. Keywords: Biosynthesis;CeO 2 ;UV-DRS;PL and Antimicrobial activity; 1. Introduction Green nanotechnology is a mushrooming area of research in the scientific world. The green approach methodsare largely unexplored and under-exploited to our knowledge. There are several biological techniques are available, the use of fruit extract for the synthesis of CeO 2 -NPsis potentially advantageous over microorganisms or plant extracts