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e246 Journal of Hypertension Vol 36, e-Supplement 1, June 2018
a significantly higher average number of risk factors (3,56 ± 0,76 vs 2,42 ± 0,96,
p < 0,0001) but no significant differences in age, body mass index and waist cir-
cumference. Abnormal OGTT was found in 55 (40 %) of patients from the first
group: 26 (19 %) had diabetes, 29 (21 %) impaired glucose tolerance. There was
no significant difference in mean creatinine and CrCl (I gr. 84,12 ± 29,97 vs II
gr.79,87 ± 27,23) between the two groups. Decline in CrCl (< 89 ml/min) was
found in 42% patients I gr. vs 50 % in II gr., < 60 ml/min in 24,5:26 %, n.s. Ab-
normal ACR was found in 41 (30 %) of patients I gr. vs 18 (33%) in II gr., n.s.
Conclusions: Conclusion: Quarter of patients with arterial hypertension and
diabetes had early renal impairment with a decrease in glomerular filtration and
about thirty percent had microalbuminuria. Patients with unknown history of dia-
betes have a high incidence of glucose metabolic disorders and subclinical renal
insufficiency. OGTT and ACR can identify individuals with subclinical disease
requiring a more aggressive treatment of risk factors and more intensive therapy.
THE PREVALENCE OF RESISTANT AND UNDERCONTROLLED
HYPERTENSION AMONG PATIENTS OF A HYPERTENSION
OUTPATIENT CLINIC IN SZEGED
L. Péter, P. Legrady, I. Fejes, G. Abraham. University of Szeged, 1st Department
of Medicine, Szeged, HUNGARY
Objective: In Hungary, between 2005–2009 around 57% of hypertensive patients
did not reach the goal blood pressure (BP).
Design and method: In one of the Hypertension Outpatient Clinics of the 1st
Department of Medicine Nephrology-Hypertension Center in Szeged 310 pa-
tients’ data were analyzed. Means of two measurements were calculated. The goal
SBP was 140/ mm Hg. Means ± SD are reported.
Results: The mean age of hypertensive patients was 61.4 ± 14.3 years. The mean
duration of HT was 14.2 ± 12.0 years. Among these 310 HT patients 115 (37%) were
men (age 58.2 ± 15.6 years) and 195 (63%) women (age 63.4 ± 13.1 years). BP of
186/310 (60%) patients were in goal range (SBP 124 ± 9 mm Hg) and 124/310 (40%)
were not (SBP 155 ± 17 mm Hg). Among the 310 patients 45 (15%) had only DM as
additional risk factor, type-1 and type-2 together. Twenty-one (17%) of 124 HT pa-
tients with undercontrolled BP had diabetes mellitus (DM) (BP 149 ± 15/89 ± 8 mm
Hg). By the definition of RHT alltogether 234/310 (76%) patients had RHT (BP
158 ± 17/97 ± 8 mm Hg) in this population. But 257/310 (83%) patients were taking
3 or more antihypertensive drugs, and their SBP was 136 ± 20 mm Hg. The difference
(n = 23) between 257 and 234 were the patients with 3 drugs but reaching the goal
SBP. With combinations of 4 or more drugs 111 of the 234 (47%) RHT patients had
BP < 140/90 mm Hg and 63 (27%) of patients with 4 or more drugs them didn’t reach
the goal BP. Among the multiple drug combinations, 83/310 (27%) patients were tak-
ing 3 antihypertensive drugs, 65/310 (21%) 4 drugs, 48/310 (15%) 5 drugs, 34/310
(11%) 6 drugs, 20/310 (6%) 7 drugs and 7/310 (2%) 8 drugs. Fifteen patients were on
monotherapy, their BP were 124 ± 12/79 ± 9 mm Hg, and only 1 of them was under-
controlled (BP 154/100 mm Hg). All the patients taking 2 drugs were in goal range.
Conclusions: A fourfold combination of antihypertensive agents was the most
frequent in this population. The most frequent drug classes were the ACEIs and/or
ARBs, the DHP-CCBs and the thiazide diuretics.
DETERMINANTS OF HYPERTENSION IN RURAL DELHI, INDIA
P. K. Gupta
1
, C. Kohli
2
, J. Kishore
3
, N. Gupta
4
.
1
Jhpiego- MNH Department, Jai-
pur, INDIA,
2
Indian Council of Medical Research, New Delhi, INDIA,
3
Vardhman
Mahavir Medical College-Department of Community Medicine, New Delhi, IN-
DIA,
4
Indian Council of Medical Research, New Delhi, INDIA
Objective: To find burden and determinants of hypertension in a rural area in Delhi.
Design and method: It was a community based cross sectional study Conducted
in two rural areas in Delhi. Study was conducted on 1005 adults aged 18 years and
above selected by systematic random sampling method over a period of one year
from July 2013 to June 2014. A pretested, predesigned, semistructured question-
naire schedule was used in local language. WHO STEPS approach was used to
study the profile of the hypertension in the population.
Results: The prevalence of hypertension was 14.1% (142/1005) among study sub-
jects. Hypertension was significantly higher in individuals more than 35 years as
compared to those less than 35 years. No significant difference with tobacco intake
was seen between both present and past tobacco users. Hypertension was significant-
ly higher in those who take alcohol, in subjects with raised total cholesterol levels, tri-
glycerides levels and among obese (p value = 0.01). In multivariate analysis only age,
education and cholesterol levels were independently associated with hypertension
Conclusions: Age, education and cholesterol levels were independent risk fac-
tors of hypertension. Education level of people should be raised and cholesterol
levels should be cut down using approaches of behaviour change communication
in the community.
LDL CHOLESTEROL CONTROL IN PATIENTS FROM A
HYPERTENSION CLINIC
P. Marques, T. Morai, M.J. Lume, S. Tavares, C. Silva, L. Nogueira-Silva,
M.J. Lima. Centro Hospitalar de S. João, Porto, PORTUGAL
Objective: The evaluation and follow up of hypertensive patients requires the consid-
eration of all cardiovascular risk factors such as the lipid profile, particularly the LDL
cholesterol. Hypertensive patients usually gather other risk factors that make them high
and very high risk patients requiring aggressive LDL control. We aimed to stratify the
cardiovascular risk profile from patients evaluated during a year and their LDL control.
Design and method: Retrospective study based on clinical records from pa-
tients evaluated in Hypertension clinic of a tertiary care hospital during a year.
Demographic, biometric and clinical data were gathered. We used the European
Society of Cardiology Heart Score to determine the category of risk in 10-years
time of our patients and also the exceptions considered in the European Society
of Cardiology guidelines. Student t tests and chi-square test were used to compare
continuous and categorical variables, respectively.
Results: A total of 228 patients, 55% females, aged 60.4 ± 15.9 were evaluated in a
year. 31 patients (13.6%) were classified as low risk, 39 (17.1%) as moderate risk, 21
(9.2%) as high risk and 133 (58.3%) as very high risk. 35% patients were classified
using Heart Score, 30% had established cardiovascular disease and 20% were diabetic
and hypertensive patients. 30% of patients did not receive a statin at the moment of
observation. Of the 144 patients classified as high or very high risk 26% didn’t receive
a statin and only 26% received a high potency statin. Association with ezetimibe was
only used at baseline in 3 patients. At baseline LDL control was accomplished in only
38% of patients. In high and very high risk patients only 19% of patients were con-
trolled at baseline. Only 23 patients from the high/very high risk population (15%) were
receiving a high potency statin and were not controlled. High salt diet, body weight, risk
category and Obstructive sleep apnea were associated with poor LDL control.
Conclusions: Many patients evaluated in our Hypertension Clinic were classi-
fied as high or very high risk patients. LDL control is markedly insufficient partly
due to unawareness and non compliance with European guidelines.
THE SPREADING OF RISK FACTORS FOR AH AMONG 29–69
YEARS FEMALE INDIVIDUALS WITH TYPE 2 DIABETES, LIVING IN
PAVLODAR
Z.Mamedguliyeva, M.K. Tundybayeva, D.D. Utebaliyeva, T.N. Leonovich,
G.A. Junusbekova, S.P. Berkinbayev, D. Mukhtarhanova. Scientific Research In-
stitute of Cardiology and Internal Diseases, Almaty, KAZAKHSTAN
Objective: To investigate the spreading of AH RF in 29–69 years women with
type 2 diabetes, who live in Pavlodar.
Design and method: The object of the study was a representative sample of
763 women aged 29–69 years, living in Pavlodar. All surveyed completed a ques-
tionnaire to identify non-specific non-communicable diseases and the presence of
bad habits, blood pressure was measured, body mass index was determined, and
laboratory studies to determine the lipid spectrum were made.
Results: The obtained results demonstrated that among the women with diabetes
the most common risk factors were cigarette smoking and low physical activity,
which reached 41.0% and 38.4% respectively. Next in frequency of occurrence is
the use of alcohol - 31,2% and excess weight of a body (BMI) - 28.1%, followed
by obesity (24.2%). Turn to lipid profile, the picture was as follows: the percentage
of patients who were diagnosed with LDL was 100%; the percentage of patients
with LDL < 2.5 mmol/L amounted to 82.5%, hypercholesterolemia (HCS) was
21.7%; hypocholesterolemia (hypo-cholesterol) - 17,9%, and hypertriglyceride-
mia (GTG) was more than 1/3 of surveyed and amounted to 36.8%.
Conclusions: The high frequency of the above-mentioned risk factors indicates
the absence of timely preventive measures, which are important in fighting hyper-
tension, which could prevent the further development of complications and the
reduction of mortality rates from heart diseases.
APBM HYPERTENSIVE INDEX TIME, IN TREATED HYPERTENSIVE
PATIENTS, CAN PREDICT VENTRICULAR REMODELING AND
CARDIOVASCULAR EVENTS
H. Rus
1
, E. Bobescu
1
, C. Dascalescu
1
, E. Grancea
2
, C. Luca
2
, I. Barsan
2
.
1
University Transilvania Brasov, Brasov, ROMANIA,
2
Emergency Hospital Bra-
sov, Brasov, ROMANIA