on coronary angiogram. Patients with normal coronary angiogram and those with mild disease were grouped under AGN, and those requiring revascularization either by PCI or Coronary artery bypass grafting were grouped under AGP. Complete blood cell counts were analyzed with auto analyzers. Red cell parameters were compared between the two groups. Statistical analysis was performed with student T test. Results: Of 765 patients, 238 were females 527 were males with mean age of 55.4 ± 11 years. Out of 765 coronary angiograms performed 438 patients were grouped under AGP and 327 pa- tients were grouped under AGN. There was no significant dif- ference between the AGP and AGN groups in mean Hemoglobin concentration (p¼0.09), Red cell count (p¼0.06), MCH (p¼0.8), MCHC (p¼0.6) but there was a statistically significant difference in MCV (p¼0.004), total leukocyte count (p¼0.007) and platelet count (p¼0.018). A positive correlation was observed with MCV, TLC, Platelet count with coronary artery disease which were significantly higher in patients with proven coronary artery disease. Conclusions: These findings suggest that altered Red blood cells may play a role in pathogenesis of coronary artery disease. This change in MCV is cause or effect is to studied. Outcome of primary angioplasty in high volume tertiary care centre Kala Jeethender Jain, Ramesh, Aditya, L.S.R. Krishna, O. Sai Satish NIZAMS Institute of Medical Sciences, Hyderabad, India Aims: To determine the outcome of primary PCI in high volume tertiary care centre. Methods: We evaluated 137 patients who underwent primary PCI for acute STEMI at our institute from JAN 2013 to DEC 2103(1 year) retrospectively. Results: A total of 137 patients were included in the study. The mean age of patients was 54.0±11.5 years. On admission, 49 patients (35.8%) had diabetes, 52 patents (38%) had hyperten- sion, 79 patients (58%) had acute AWMI, and 66 patients (48.7%) were smokers. Cardiogenic shock, complete heart block, ven- tricular fibrillation were encountered in 8 patients (5.7%), 10 patients (7.2%) and 12 patients (8.9%) respectively at hospital admission. The mean door-to balloon time was 62.5±15 minutes. Infarct related artery was eLAD (58%), LCX (12%), and RCA (30%) of pa- tients. Multivessel disease was seen in 12 patients (6.4%). POBA was done in 5 patients (3.9%) and rest of the patients had stent implantation. The incidence of angiographic no reflow was seen in 5 patients (3.9%). The mean hospital stay was 5.2±3.3 days. During hospital stay, the in hospital mortality was 5 patients (3.6%) out of which 4 patients (2.8%) died of a cardiac cause. Target vessel revascularization, major bleeding and minor bleeding were observed in 1(1.1%), 1(1.1%) and 3(2.2%) respectively. Acute stent thrombosis occurred in 1 patient (1.2%). Conclusion: Primary PCI is an effective method in achieving complete revascularization of infarct related artery. Successful in hospital results depend not only on the experience of the oper- ator, but also on the rapidity of reperfusion. Relationship between Diabetes and Syndrome X in women with stable angina T. Ganesh, M.S. Ravi, K. Meenakshi, D. Muthukumar, N. Swaminathan, G. Ravishankar, G. Justin Paul, C. Moorthy, G. Prathap Kumar, S. Venkatesan Madras Medical College, Chennai, India Background: Cardiac Syndrome X describes patients with angina, compatible findings with myocardial ischemia and normal coro- nary angiograms. It is an important clinical entity that should be distinguished from ischemic heart disease caused by obstructive coronary artery disease. Aims: Several studies have already established the predominance of Syndrome X in female population. In our study, we analyse the prevalence of Syndrome X in female population and the signifi- cance of age, menopausal status, diabetes and hypertension with syndrome X. Methods: This is a observational study conducted in the Depart- ment of Cardiology in a tertiary care centre in Chennai during the period of May to July 2014. A total of 50 female patients with anginal symptoms and evidence of myocardial ischemia in the form of positive treadmill test by Bruce protocol were included. They underwent diagnostic coronary angiogram. The pattern of coronary artery involvement was analysed. Results: Out of the 50 female patients who underwent coronary angiograms, 20 (40%) patients had normal coronary arteries. Of these 20 patients, 16 (80%) were post-menopausal and 4 (20%) were pre-menopausal. Diabetic population among the patients with normal coronaries were 12 (60%), hypertensive non-diabetic population were 5 (25%) patients, non-diabetic non-hypertensive population were 3 (15%) patients. Average age among patients with normal coronary angiogram was 54 years, with average age being lower in diabetics (52 years) compared to non diabetics (58 years). Conclusion: Cardiac syndrome X has a higher prevalence in fe- male population in the post menopausal age group. Diabetic population was associated with greater incidence of syndrome X with a lower average age compared to non diabetic women. The analysis of diabetic and non-diabetic patients with cardiac syn- drome X in this study has shown that diabetic population has a greater involvement of coronary microcirculation at an earlier age. Does the antiplatelet regimen needs a change in CKD patients: a platelet inhibition study K.V. Siva Krishna, M. Jyotsna, D. SeshaGiri Rao, B. Srinivas, Rama Kumari, A. Siva Prasad, R.C. Barik, Lalitha Nizams Institute of Medical Sciences, Hyderabad, India Background: Higher coronary in-stent thrombosis and bleeding complications on anti-platelet agents are more common in Chronic Kidney Disease vs. non-Chronic Kidney Disease patients. Poor inhibition of platelet aggregation by anti-platelet agents predicts future cardiovascular events. Clinical practice guidelines are ambiguous about the use of these agents in Chronic Kidney Disease due to lack of controlled studies. The investigators indian heart journal 66 (2014) s1 es143 S24