Accepted Article Title: Efficacy of Peritoneal Dialysis in Neonates Presenting With Hyperammonaemia Due to Urea Cycle Defects and Organic Acidaemia Running title: Peritoneal Dialysis in Hyperammonaemia Muhittin Celik 1 , Osman Akdeniz, Nezir Ozgun Muhittin Celik: M.D. Diyarbakir Children’s Hospital, Department of Pediatrics, Division of Neonatology, Diyarbakir, Turkey. Email: mehdincelik@hotmail.com Osman Akdeniz: M.D. Diyarbakir Children’s Hospital, Department of Pediatrics, Division of Pediatric Cardiology, Diyarbakir, Turkey. Email: osman_akdeniz@gmail.com Nezir Ozgun:M.D. Diyarbakir Children’s Hospital, Department of Pediatrics, Division of Pediatric Neurology, Diyarbakir, Turkey.Email: nezirozgun@hotmail.com Corresponding Author: Dr. Muhittin Çelik Diyarbakir Children’s Hospital, Department of Pediatrics, Division of Neonatolog. 21100 Yenisehir mah, Diyarbakir/Turkey. E-mail: mehdincelik@hotmailcom Tel: +90 4122245751, Fax: +90412 228 7758 Aim: Newborns with inborn errors of metabolism can present with hyperammonaemic coma. In this study, we evaluated the effect of peritoneal dialysis on plasma ammonium levels and on the short-term outcome in neonatal patients with urea cycle defects and organic acidaemia. This article is protected by copyright. All rights reserved. This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/nep.13224