This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/bab.1768. This article is protected by copyright. All rights reserved. Graphene oxide-L-arginine Nano-gel: a pH-Sensitive Fluorouracil Nanocarrier Short title: Graphene oxide-L-arginine Nanogel Hanieh Malekimusavi 1 , AmirHossein Ghaemi 2 , Ghasem Masoudi 3 , Faraz Chogan 2 , Hamid Rashedi * ,1 , Fatemeh Yazdian * ,2 , Meisam Omidi 4,5 , Shohreh Javadi 6 , Bibi Fatemeh Haghiralsadat 7 , Masoumeh Teimouri 2 , Naghmeh Faal Hamedani 8 1 Department of Biotechnology, School of Chemical Engineering, College of Engineering, University of Tehran, Tehran, Iran 2 Department of Life Science Engineering, Faculty of New Science and Technologies, University of Tehran, Tehran, Iran 3 Department of Chemical and Petroleum Engineering, Sharif University of Technology, Tehran, Iran 4 Protein Research Centre, Shahid Beheshti University, GC, Velenjak, Tehran, Iran 5 Marquette University School of Dentistry, Milwaukee, WI, USA 6 Department of Chemical Engineering, Ferdowsi University of Mashhad, Mashhad, Iran 7 Department of Advanced Medical Sciences and Technologies, School of Paramedicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran 8 Department of Chemistry, Faculty of Valisar, Tehran Branch, Technical and Vocational University (TVU), Tehran, Iran * Corresponding authors: hrashedi@ut.ac.ir, Yazdian@ut.ac.ir