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SUPPORTING INFORMATION
Investigation of triazole linked indole and oxindole glycoconjugates as
potential anticancer agents: Novel Akt/PKB signaling pathway inhibitors
Atulya Nagarsenkar
a
, Santosh Kumar Prajapti
a
, Sravanthi Devi Guggilapu
a
, Swetha Birineni
b
,
Sudha Sravanti Kotapalli
b
, Ramesh Ummanni
b*
and Bathini Nagendra Babu
a*
a
Department of Medicinal Chemistry, National Institute of Pharmaceutical Education&
Research (NIPER), Balanagar, Hyderabad 500037, India;
b
Center for Chemical Biology,
Indian Institute of Chemical Technology (CSIR-IICT), Tarnaka, Hyderabad 500007, India.
*Corresponding Author: Tel.: +91 40 23073740; Fax: +91 40 23073751; E-mail address:
bathini.niperhyd@gov.in
Content
General experimental procedure and spectral data for compounds 5(a-k), E-9(a-j) and
Z-9(a-j)…...............................................................................................2-14
Experimental protocol for SRB assay, change in morphology, colony formation assay
(soft agar assay), cell cycle analysis, determination of activation of caspase and
western blotting……………………………….………………..................15-17
Electronic Supplementary Material (ESI) for MedChemComm.
This journal is © The Royal Society of Chemistry 2016