_____________________________________________________________________________________________________ *Corresponding author: E-mail: djyhbn@gmail.com; International Journal of Biochemistry Research & Review 29(1): 20-33, 2020; Article no.IJBCRR.54132 ISSN: 2231-086X, NLM ID: 101654445 Effects of Repeated Administration of Extracts from Arachis hypogaea Hulls on Blood Parameters and Histological Organization of Heart, Liver and Kidneys of Rats Djyh Bernard Nazaire 1* , Tra Bi Irié Otis 2 , Oungbé Monkoué Désiré 1 , Gnahoué Goueh Laurent 2 , Kra Adou Koffi Mathieu 1 , D’almeida Marie-Anne Kayi 3 and Djaman Allico Joseph 1,4 1 Laboratory of Biochemical Pharmacodynamics, UFR Biosciences, Université Félix Houphouët- Boigny, Cocody, 22 BP 582 Abidjan, Côte d’Ivoire. 2 Superior Normal School Abidjan, ENS, Abidjan 08, Côte d’Ivoire. 3 Laboratory of Cellular Biology, UFR Biosciences, UFR Biosciences, Université Félix Houphouët- Boigny, Cocody, 22 BP 582 Abidjan, Côte d’Ivoire. 4 Department of Medical and Basic Biochemistry, Institute Pasteur of Côte d'Ivoire, 01 BP 490 Abidjan 01, Côte d’Ivoire. Authors’ contributions This work was carried out in collaboration among all authors. Authors DBN and DMAK designed the study. Author DBN performed the statistical analysis, wrote the protocol, managed the literature searches and wrote the first draft of the manuscript. Authors DMAK and OMD managed the histological study. Authors TBIO and GGL helped for the animal experimentation. Author KAKM managed the proofreading of the manuscript. Author DAJ assisted in the design of the study and helped in hematological and biochemical analysis. All authors read and approved the final manuscript. Article Information DOI: 10.9734/IJBCRR/2020/v29i130162 Editor(s): (1) Dr. Enrico Sanjust, Associate Professor, Department of Biomedical Sciences, University of Cagliari, Italy. Reviewers: (1) Charles Emeka Umenwa, University of Ibadan, Nigeria. (2) Sandra Machado Lira, Centro Universitário Maurício de Nassau, Brasil. Complete Peer review History: http://www.sdiarticle4.com/review-history/54132 Received 20 November 2019 Accepted 27 January 2020 Published 19 February 2020 ABSTRACT Aims: Arachis hypogaea (peanuts) is widely used in food worldwide. Therapeutic use of various parts of this plant has been mentioned in many traditional medicinal systems. The aim of the present study was to evaluate subacute toxicity of methanolic and aqueous extracts of peanuts hulls. Original Research Article