International Journal of Nursing June 2019, Vol. 6, No. 1, pp. 72-82 ISSN 2373-7662 (Print) 2373-7670 (Online) Copyright © The Author(s). All Rights Reserved. Published by American Research Institute for Policy Development DOI: 10.15640/ijn.v6n1a8 URL: https://doi.org/DOI: 10.15640/ijn.v6n1a8 The Efficiency of Evidence-Based Guidelines on Performance, Perception, and Satisfaction of Patients Undergoing Bone Marrow Biopsy Samia Eaid Elgazzar 1 , Shereen Ahmed Ahmed Qalawa 2 , & Shreen Ibrahim Eltahry 3 Abstract Background: Bone marrow biopsy plays a critical role in the identification and management of several hematological and systemic illnesses. Even although the procedure has been conceded for years, it remains uncomfortable and extremely painful experience for all patients. While applying evidence-based guidelines in dealing with a patient undergoing bone marrow biopsy is not only an absolute duty for nurses practicing, however, is too a central role to the nursing science. Objectives: This study aims to assess and evaluate the impact of evidence-based guidelines on performance, perception, and satisfaction of patients undergoing bone marrow biopsy Method: Quasi-experimental research design was conducted. The purposive sample for all patients (50) admitted for Bone Marrow biopsy with various hematological disorders at Damietta Oncology Institute. The instrument was used to collect study data include patient socio-demographic, health information characteristics, patient's performance, the perception of patient's and satisfaction. Result: It showed that the majority of patients had a higher total mean score at post-evidence-based guidelines implementation than pre implementing of guidelines regarding patient's perception, performance, and satisfaction with statistically significant difference (p ≤ 0.05).Conclusion: Evidence-based guidelines improve patient's perception, performance, and satisfaction regarding bone marrow biopsy. Recommendations: Activate implementation of bone marrow biopsy an aspiration guidelines manual in the hospitals and it's availability to all patients in the simple media and language. Also, nurses must be trained to implement evidence-based guidelines. This study may deliver a performance framework for the future advance in other nursing evidence-based practice. Keyword: Evidence-based Guidelines, Performance, Perception, Satisfaction, Bone Marrow Biopsy 1. Introduction Bone marrow biopsy (BMB) is an essential diagnostic procedure to the identification of disorders in hematological, on-hematological disease and follow-up assessment of patients who experience chemotherapy, transplantation bone marrow and additional techniques of medical treatment (Hjortholm et al., 2013, Omar et al., 2014&katiyar, 2017,). It is a safe technique; the related hazard is low (about 0.1%) and not reliant on operator experience (Bain et al., 2011. It was established at the start of the nineteenth century, permitting doctors to identify marrow disorders in patients. The procedure progressed in the subsequent years with an emphasis on repeatable and easier of bone marrow collection, foremost to complete standardization of the technique in the 1970s (Hjortholm et al., 2013). Moreover, as contemporary medicine develops tailored and patient-oriented to confirm every patient grows extreme advantage from the healthcare personnel, the significance is assumed to decrease pain related with medical practices/interventions. Since there is a scarcity of data regarding the treatment and avoidance of problems during BMB, strategies to fight this problem have not been outlined (Zahid, 2015, Hjortholm et al., 2013). 1 Lecturer, Medical-Surgical Nursing, Faculty of Nursing, Port-said University. Egypt. E-mail: adamramy36@yahoo.com 2 Assistant Professor, Medical-Surgical Nursing, Faculty of Nursing, Port-said University. Egypt. 3 Lecturer, Medical-Surgical Nursing, Faculty of Nursing, Port-said University. Egypt.