Vol.:(0123456789)
Research on Chemical Intermediates
https://doi.org/10.1007/s11164-020-04234-4
1 3
Synthesis and characterization of the immobilized
polythiophene on magnetic carbon nanotube
as a prominent catalyst for the synthesis
of dihydropyrimidinone and octahydroquinazolinone
derivatives
Parisa Akbarzadeh
1
· Nadiya Koukabi
1
Received: 3 May 2020 / Accepted: 5 August 2020
© Springer Nature B.V. 2020
Abstract
In this work, the immobilized polythiophene on magnetic carbon nanotube (CNT–
Fe
3
O
4
–PTh) was synthesized and introduced as a novel and recoverable catalytic
system. The prepared magnetic heterogeneous nanocatalyst was characterized by
FT-IR, TGA, EDX, VSM, XRD, TEM, and FE-SEM. Next, the catalytic efciency
of CNT–Fe
3
O
4
–PTh was evaluated through the green synthesis of a variety of dihy-
dropyrimidinone and octahydroquinazolinone through Biginelli reaction between
aromatic aldehydes, urea/thiourea, and β-dicarbonyl compounds under solvent-free
conditions. The catalyst was magnetically recovered and recycled for fve cycles
without a discernible loss in its catalytic activity. Simple workup, afordability, short
reaction times, mild reaction conditions, and the high yield of products are the inter-
esting features of this project.
Graphic abstract
An environmentally benign nanocomposite was prepared using carbon nanotube as
an inexpensive, nontoxic, and stable support in the preparation of CNT–Fe
3
O
4
–PTh,
which was efciently used as catalyst for the green synthesis of dihydropyrimidinone
Electronic supplementary material The online version of this article (https://doi.org/10.1007/s1116
4-020-04234-4) contains supplementary material, which is available to authorized users.
* Nadiya Koukabi
n.koukabi@semnan.ac.ir
1
Department of Chemistry, Semnan University, Semnan 35131-19111, Iran