PII S0730-725X(97)00240-3 Original Contribution PARAMAGNETIC TRACER CONCENTRATION EVOLUTION BY NMR RELAXATION TIME MAPPING: APPLICATION TO ARIS-TAYLOR DISPERSION Y.E. KUTSOVSKY,* V. ALVARADO,* L.E. SCRIVEN,* H.T. DAVIS,* AND B.E. HAMMER *Department of Chemical Engineering and Materials Science, and †Department of Radiology, University of Minnesota, Minneapolis, MN 55455 A procedure to study tracer dispersion was proposed and tested for the case of tracer spreading in tube flow. Concentration maps of paramagnetic tracers Gd 3 were measured in time through direct measurements of spin lattice relaxation time T 1 obtained by using a two-point stimulated echo pulse sequence. The procedure was used to test the linear dependence of Peclet number on inverse velocity in the range of flow rates 0.3–1.2 cc/min. © 1998 Elsevier Science Inc. INTRODUCTION The spreading of particles in fluids under the combined action of convection and molecular diffusion is called dispersion. The phenomenon occurs, for example, when two fully miscible fluids are brought into contact and the concentration fronts are spread by convection and mo- lecular diffusion. 1 Such spreading is of great importance in technological applications such as oil recovery, envi- ronmental science and chemical engineering. Dispersion in steady flow is the subject here. It is commonly studied by using tracers. Once steady-state flow with mean velocity U is established, a tracer is released in the fluid at the inlet section of the sample of interest and the mean tracer concentration is measured as a function of time or position. A typical dispersion ex- periment is sketched in Fig. 1. The output profile is a function of the shape of the input profile and the tracer spreading by flow and diffusion in the sample. The evolution of tracers in the typical dispersion experiment is commonly described by the one-dimen- sional convection-dispersion equation C t + U C z = D 2 C z 2 (1) This equation looks like the convection-diffusion equa- tion, but D is not the diffusivity. It is the axial dispersion coefficient. This analogous quantity is a strong function of both the flow properties and the molecular diffusivity. The concentration C is the cup-mixed mean, i.e., the cross-sectional average not the local concentration value. Very few data have been published that yield the value of the dispersion coefficient. One well-known case is tracer dispersion in Poiseuile flow, which was analyzed theo- retically by Taylor, 1953 2 and Aris, 1956. 3 This case is commonly referred to as Taylor dispersion or Taylor- Aris dispersion. With the contribution of axial molecular diffusion included, Taylor’s formula for the axial disper- sion coefficient D in a tube of circular cross-section with radius R is: D = D m + U 2 R 2 48D m (2) D m is the molecular diffusivity. Acoustic 4 or electrical 5 detection techniques are often employed to measure tracer concentration, but their spa- tial resolution is limited to a few millimeters. To over- come limitations in spatial resolution, nuclear magnetic resonance (NMR) has been used to track paramagnetic agents in liquid. 6,7 Concentration of paramagnetic tracers can be deduced from signal intensity, which is a function of spin-lattice relaxation time, T 1 . 8 The ability to determine dispersion properties of a RECEIVED 7/31/96; ACCEPTED 8/29/97. Address correspondence to Dr. B. Hammer, University of Minnesota, Cntr. Interdisciplinary Appl. Mag. Res., Department of Radiology, Box 292 Mayo, 420 Delaware Street, S.E., Minneapolis, MN 55455 USA. E-mail: hammer@ciamr.umn.edu Magnetic Resonance Imaging, Vol. 16, No. 1, pp. 63–71, 1998 © 1998 Elsevier Science Inc. All rights reserved. Printed in the USA. 0730-725X/98 $19.00 + .00 63