Acta Scientific MEDICAL SCIENCES (ISSN: 2582-0931) Volume 5 Issue 7 July 2021 Assessment of Pancreatic Sizes in Patients with Diabetes Mellitus: An Ultrasound Based Study Iqra Ilyas* Department of Radiological Sciences and Medical Imaging, Faculty of Health and Allied Sciences, Imperial College of Business Studies - Lahore, Pakistan *Corresponding Author: Iqra Ilyas, Department of Radiological Sciences and Medical Imaging, Faculty of Health and Allied Sciences, Imperial College of Business Studies - Lahore, Pakistan. Research Article Received: June 03, 2021 Published: June 15, 2021 © All rights are reserved by Iqra Ilyas. Abstract Aims and Objectives: To evaluate the pancreatic size in diabetic patients and compare them with regular patients. Methodology: A prospective comparative study was conducted for six months, and 102 patients were included. Patients of type1DM, type2DM and control subjects were selected. The pancreas' ultrasound was performed on 27 healthy patients, 33 were with type 1 (Insulin-dependent diabetes mellitus), and 42 were type 2 (Non-insulin-dependent diabetes mellitus). Standard parameters of pan- creatic size such as pancreatic head, pancreatic body, and pancreatic tail have been measured. The statistical analysis was performed using MedCalc. Results: The results show that the mean age was 37 years in the control group, the mean age was 50 years in the NIDDM group, and the mean age was ten years in the IDDM group. 37% were women, and 63% were men in the control sample. Although 36.4% were females and 63.6% in the IDDM community were males. Fifty-two percent were women, and in the NIDDM, 47 percent were men. Conclusion: Pancreatic size shows a decrease in type1DM and type2DM as compared to the control group. T1DM shows more notice- able changes compared to T2DM. Keywords: Pancreatic Size; Insulin-dependent Diabetes Mellitus; Non-insulin Dependent Diabetes Mellitus; Ultrasound Introduction In every medical assessment of the abdomen by a practitioner, measurement of pancreatic size is essential. A category of specific metabolic diseases that associate the hyperglycemia phenotype includes Diabetes mellitus (DM). Over the previous two centuries, the global incidence of diabetes has significantly increased [1]. The pancreas is one of the organs producing juices, and enzymes found hidden throughout the abdominal cavity and distributed be- hind the stomach. Before becoming consumed by the stomach, the pancreas' enzymes assist in metabolizing fats, proteins, and car- bohydrates. Insulin, which is essential in controlling the amount of glucose in the body, is also produced by the pancreas. Multiple conditions, including diabetes mellitus, acute pancreatitis, chronic pancreatitis, and pancreatic enzyme depletion, and pancreatic tumors, can contribute to every system malfunction or abnormal- ity that develops in the pancreas [2]. Diabetes is a form of disease correlated with an unnaturally high blood sugar glucose concen- tration; no insulin or inappropriate reaction to insulin secretion is made [3]. Diabetes is the most common disorder associated with the pancreas. It has the following two types: Type 1 insulin-de- pendent diabetes mellitus (IDDM) is also called juvenile diabetes because it affects children and adults [4]. It occurs because insulin- producing beta cells do not work or make insulin [5]. It is evaluated that approximately 80,000 children develop this form of diabetes each year [6]. Type 2 is non-insulin-dependent diabetes mellitus (NIDDM) [7]. It occurs either by reduced insulin secretions or in- sulin resistance. In this type, pancreatic beta cells don't respond appropriately to insulin secretions [8,9]. The pancreas is a unique organ because it has the dual function of secreting hormones into blood (endocrine) and secretes hormones through ducts (exocrine) [10]. Pancreases has a cluster of irregular-shaped endocrine cells, which are called Islet of Langerhans [11]. These islets of Langer- hans contain different types of cells. In which the insulin-producing beta cells are in significant numbers [12]. Beta cells are responsible Citation: Iqra Ilyas. “Assessment of Pancreatic Sizes in Patients with Diabetes Mellitus: An Ultrasound Based Study". Acta Scientific Medical Sciences 5.7 (2021): 44-52.