International Journal of Sciences: Basic and Applied Research (IJSBAR) ISSN 2307-4531 (Print & Online) http://gssrr.org/index.php?journal=JournalOfBasicAndApplied --------------------------------------------------------------------------------------------------------------------------- 26 Factors Related to the Work Stress of Nurses During the Covid-19 Pandemic in the Inpatient Rooms of Tk.II Marthen Indey Hospital Ika Wijayanti a , Novita Medyati b* , Yacob Ruru c a Postgraduate Master Program of Public Health, Faculty of Public Health, Cenderawasih University b Faculty of Public Health, Cenderawasih University, Jayapura Papua, Indonesia, 99351 c Department of Satistics, Faculty of Mathematics and Natural Sciences, Cenderawasih University a Email: ikawijayanti2606@gmail.com; b Email: novitamedyati2021@gmail.com Abstract Background: COVID-19 cases are increasing and nurses are at the forefront of handling COVID-19 patients, so they are at risk of contracting COVID-19. Data at Tk.II Marthen Indey Hospital, there were 12 nurses who tested positive for COVID-19. Lack of personal protective equipment affects nurses in carrying out their duties and work, this condition causes nurses to have pressure on their work which affects their physical, mental and social conditions. Objective: The purpose of this study was to determine the factors associated with the work stress of nurses during the COVID-19 pandemic in the inpatient room of Tk.II Marthen Indey Hospital.. Methods: This type of research is quantitative analytic with a cross sectional study design. This research was conducted at Tk.II Marthen Indey Hospital in an inpatient room which began in December 2020-January 2021. The population in this study were all nurses in the inpatient room of Tk.II Marthen Indey Hospital, with a sample using a total population of 85 people. Collecting data using online questionnaires, and processing and analyzing data for bivariate analysis using the Chi-square test, while to determine the dominant factor using multivariate analysis using logistic regression test with p-value = 0.05 with 95% CI. Results: The results showed that there was a relationship between workload (p-value = 0.000) and job satisfaction (p-value = 0.020) with work stress. ------------------------------------------------------------------------ * Corresponding author.