This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/dth.14193 Diagnosis and treatment of melanoma bone metastasis: a multidisciplinary approach Antonio Caldaria 1 , MD; Roberta Giuffrida 2 , MD, PhD; Nicola Di Meo 3 , MD; Leo Massari 1 , MD; Caterina Dianzani 4 , MD, PhD; Serafinella Patrizia Cannavò 2 , MD; Ferruccio Degrassi 5 , MD; Edoardo Casablanca 6 , MD; Iris Zalaudek 3 , MD; Claudio Conforti 3 , MD 1 Orthopedic and Traumatology Unit, Sant’Anna University Hospital, Ferrara, Italy 2 Department of Clinical and Experimental Medicine, Dermatology, University of Messina, Messina, Italy. 3 Dermatology Clinic, Hospital Maggiore of Trieste, University of Trieste, Italy 4 Plastic Surgery Unit, Section of Dermatology, Campus Biomedico University, Rome, Italy 5 Department of Radiology, Maggiore Hospital of Trieste, University of Trieste, Trieste, Italy 6 Department of Orthopedics and Trauma Surgery, University of Verona, Italy Corresponding author: Dr. Roberta Giuffrida, MD, PhD Department of Clinical and Experimental Medicine, Dermatology, University of Messina, Italy via Consolare Valeria n°1, 98125 Messina, Italy. Telephone number: +39 090 2212891 Fax number: +39 0902927691. Email: roberta_giuffrida@hotmail.it Article type: Review Running head: management of melanoma bone metastasis Funding source: none declared This article is protected by copyright. All rights reserved. Conflict of interest disclosure: the authors have no conflict of interest to disclose