Accepted Manuscript Investigation of the synergistic effects of paclitaxel and herbal substances and endemic plant extracts on cell cycle and apoptosis signal pathways in prostate cancer cell lines Zeynep Özlem Doğan Şiğva, Tuğçe Balci Okcanoğlu, Çığır Biray Avci, Sunde Yilmaz Süslüer, Çağla Kayabaşi, Burak Turna, Yavuz Dodurga, Oktay Nazli, Cumhur Gündüz PII: S0378-1119(18)31192-2 DOI: https://doi.org/10.1016/j.gene.2018.11.049 Reference: GENE 43394 To appear in: Gene Received date: 29 August 2018 Accepted date: 15 November 2018 Please cite this article as: Zeynep Özlem Doğan Şiğva, Tuğçe Balci Okcanoğlu, Çığır Biray Avci, Sunde Yilmaz Süslüer, Çağla Kayabaşi, Burak Turna, Yavuz Dodurga, Oktay Nazli, Cumhur Gündüz , Investigation of the synergistic effects of paclitaxel and herbal substances and endemic plant extracts on cell cycle and apoptosis signal pathways in prostate cancer cell lines. Gene (2018), https://doi.org/10.1016/j.gene.2018.11.049 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.