105 President, Staff Society N. A. Kshirsagar Editor Atul Goel Associate Editors Sandeep Bavdekar Lakshmi Rajgopal Consulting Editors Nithya Gogtay Sanjay Mehta Vinita Salvi Managing Editor D. K. Sahu Members Amita Athavale Abhay Dalvi Sucheta Dandekar Hemant Deshmukh Anil Patwardhan Preeti Mehta Nalini Shah Lalita Tuteja Pradeep Vaideeswar S. V. Vaidya Editorial Assistants Shilpa Abhyanakar Jignesh Gandhi Milind Tullu Statistical Advisor Anil Arekar Copy Editors Akshar Editorial Office Department of Neurosurgery, Seth G. S. Medical College and K. E. M. Hospital, Parel, Mumbai - 400 012, India Administrative Office Medknow Publications, 12, Manisha Plaza, M. N. Road, Kurla (W), Mumbai - 400 070, India Phone: 91-22-2503 2970 Fax: 91-22-2503 2398 E-mail - jpgm@jpgmonline.com Websites http://www.jpgmonline.com https://journalonweb.com/jpgm http://www.bioline.org.br/jp Journal of Postgraduate Medicine Volume 49, Issue 2, April-June, 2003 Print ISSN 0022-3859 CD ISSN 0972-2823 Contents Editorial Antibiotic resistance: Unless we act soon! Bavdekar SB ...................................................................................................................................... 107 Original Article Original Articles Recruitment of subjects for clinical trials after informed consent: Does gender and educational status make a difference? Gitanjali B, Raveendran R, Pandian DG, Sujindra S .......................................................................... 109 Brief Reports Human immunodeficiency virus type 1 infection in patients with severe falciparum malaria in urban India Khasnis AA, Karnad DR ..................................................................................................................... 114 Antimicrobial-induced endotoxaemia in patients with sepsis in the field of acute pyelonephritis Giamarellos-Bourboulis EJ, Perdios J, Gargalianos P, Kosmidis J, Giamarellou H ............................. 118 A comparison of intravenous ketoprofen versus pethidine on peri-operative analgesia and post-operative nausea and vomiting in paediatric vitreoretinal surgery Subramaniam R, Ghai B, Khetarpal M, Subramanyam MS ............................................................... 123 Extended interval between enzyme therapy infusions for adult patients with Gaucher’s disease type 1 Pérez-Calvo J, Giraldo P, Pastores GM, Fernández-Galán M, Martín-Nuñez G, Pocoví M .................. 127 Umbilical hernia in adults: Day case local anaesthetic repair Menon VS, Brown TH ........................................................................................................................ 132 Special Articles Tuberculosis: Looking beyond BCG vaccines Mustafa Abu S, Al-Attiyah Raja .......................................................................................................... 134 Smallpox: Clinical highlights and considerations for vaccination Mahoney MC, Symons AB, Kimmel SR .............................................................................................. 141 Case Reports Laparoscopic bilateral nephroureterectomy and bladder cuff excision for native renal pelvic and ureteral transitional cell carcinoma after renal transplantation Chen CH, Huan SK, Lin JT, Chiu AW ................................................................................................ 148 Meckel’s diverticulum: An alter native conduit for the Mitrofanoff procedure Prabhakaran K, Patankar JZ, Mali V ................................................................................................... 151 Prenatal diagnosis of partial trisomy 21 associated with maternal balanced translocation 46xx der 21 t(21q;22q) with pericentric inversion of chromosome 9 Parmar RC, Sira P .............................................................................................................................. 154 Colonic adenocarcinoma presenting as a cutaneous metastasis in an old operative scar Wright PK, Jha MK, Barrett PD, Bain IM ............................................................................................ 157 Ethics-Forum Ethics of patient care by trainee-doctors in teaching hospitals Sethuraman KR .................................................................................................................................. 159