Open Journal of Medical Microbiology, 2018, 8, 109-117
http://www.scirp.org/journal/ojmm
ISSN Online: 2165-3380
ISSN Print: 2165-3372
DOI: 10.4236/ojmm.2018.84010 Nov. 21, 2018 109 Open Journal of Medical Microbiology
Infection of Toxoplasma gondii in Humans and
Livestock Animals: An Emerging Silent Threat
for Bangladesh
Taibur Rahman
*
, Atiqur Rahman, Sajib Chakraborty
Department of Biochemistry and Molecular Biology, University of Dhaka, Dhaka, Bangladesh
Abstract
Toxoplasma gondii is an intracellular, zoonotic protozoan parasite that causes
toxoplasmosis. It can potentially infect almost all mammalian and avian hosts
including one-third of the human population world-wide. The major target
group of the parasite includes immunocompromised patients (e.g. AIDS,
cancer, organ transplantation) and fetus bearing pregnant women where it
develops toxoplasmic encephalitis, myocarditis, chorioretinitis and abnormal
fetal brain development or stillbirths respectively. In this review, we have
presented the current status of T. gondii infection in livestock animals and
human population in Bangladesh to assess the country-wide relative risk. Al-
though exact prevalence is difficult to predict due to the scarcity of data, nev-
ertheless existing literature suggests that 16% - 39% humans and 8% - 70%
domestic animals are infected with T. gondii, which implies Bangladeshi
population is at high risk of toxoplasmosis. Furthermore, we have proposed a
potential area of research to decipher the genetic diversity and transmission
routes of T. gondii infection into Bangladeshi population.
Keywords
Toxoplasma gondii, Seroprevalence, Livestock Animals, Humans, Bangladesh
1. Introduction
Toxoplasma gondii is an important zoonotic protozoan parasite that can infect
any warm blooded animals including humans and causes toxoplasmosis [1]. T.
gondii belongs to the group of phylum Apicomplexa that was first identified in
African rodent “Ctenodactylus gundii” in 1908 by Nicolle and Manceaux at Pas-
teur institute of Tunis. T. gondii is widely distributed in nature and therefore in-
How to cite this paper: Rahman, T., Rah-
man, A. and Chakraborty, S. (2018) Infection
of Toxoplasma gondii in Humans and Lives-
tock Animals: An Emerging Silent Threat for
Bangladesh. Open Journal of Medical Micro-
biology, 8, 109-117.
https://doi.org/10.4236/ojmm.2018.84010
Received: September 12, 2018
Accepted: November 5, 2018
Published: November 21, 2018
Copyright © 2018 by authors and
Scientific Research Publishing Inc.
This work is licensed under the Creative
Commons Attribution International
License (CC BY 4.0).
http://creativecommons.org/licenses/by/4.0/
Open Access