35 Autumn 2020. Volume 1. Number 4 Yazdan Ghandi 1* , Sarvenaz Mehrabi 2 , Mohammadreza Safaei Qomi 3 1. Department of Pediatric Cardiology, Amir Kabir Hospital, School of Medicine, Arak University of Medical Sciences, Arak, Iran. 2. Department of Pediatrics, Amir Kabir Hospital, School of Medicine, Arak University of Medical Sciences, Arak, Iran. 3. Department of Pediatrics, School of Medicine, Arak University of Medical Sciences, Arak, Iran. * Corresponding Author: Yazdan Ghandi, PhD. Address: Department of Pediatric Cardiology, Amir Kabir Hospital, School of Medicine, Arak University of Medical Sciences, Arak, Iran. Phone: +98 (937) 8344116 E-mail: drghandi1351@gmail.com Case Report: Premature Neonate With Subclinical Myocarditis Born to a Mother With COVID-19 Infection: A Case Report Background: In December 2019, COVID-19 caused by the SARS-CoV-2 appeared in China and then spread to many countries. Like many other medical conditions, infection with SARS CoV-2 would cause complications during pregnancy and severe illness in pregnant women. Case Report: We reported a premature neonate (31 weeks gesational age, weight 1700 g) with subclinical myocarditis born to a mother with COVID-19. Her mother had no symptoms and confrmed infection with SARS CoV-2 during pregnancy. Four days after delivery, the mother was diagnosed with COVID-19 infection. The neonate had positive C-Reactive Protein (CRP), elevated cardiac enzymes, and lymphopenia but negative real-time Polymerase Chain Reaction assays (real-time PCR). Her subclinical myocarditis was treated with Intravenous Immunoglobulin (IVIG) and inotrope. We did not use antiviral therapy in medical treatment. The neonate was discharged 3 weeks after admission with normal cardiac biomarkers enzyme levels and cardiac function in echocardiography. Her follow-up ches x-ray after two weeks was also normal. Conclusion: It seems that subclinical myocarditis can be a complication of COVID-19 in neonates, and this infection could also cause preterm labor in infected pregnant women. Since clinical data on COVID-19 in newborns are sill very limited, it is essential to check all the potential complications for pregnant women and their newborns, including cardiac complications. A B S T R A C T Keywords: COVID-19, SARS-Cov-2, Myocarditis, Premature neonate Please cite this article as Ghandi Y, Mehrabi S, Safaei Qomi M. Premature Neonate With Subclinical Myocarditis Born to a Mother With COVID-19 Infection: A Case Report. Journal of Vessels and Circulation. 2020; 1(4):35-40. http://dx.doi. org/10.29252/jvesselcirc.1.4.35 : http://dx.doi.org/10.29252/jvesselcirc.1.4.35 Use your device to scan and read the artcle online Article info: Received: 13 Apr 2020 Accepted: 08 Aug 2020 Publish: 01 Oct 2020