© ADR Journals 2017. All Rights Reserved. Research Artcle Dengue Sero-surveillance in Delhi: A Community-Based Study Shantanu Sharma 1 , VK Gupta 2 , Anita Chakravarty 3 , Suneela Garg 4 Abstract Background: IgG ELISA is useful as an epidemiological tool when used to establish sero-prevalence. Extensive background informaton is required before selectng sites for dengue vaccine trials like types of dengue virus that are causing disease, preferably over a number of years, sero-prevalence of dengue IgG antbodies, prevalence of each serotype, rates of infecton, specifc mortality, etc. Aims and Objectves • To study the prevalence of dengue IgG antbodies in the serum of adults in urban slums of Delhi • To study the knowledge, attude and the practce of study subjects about the preventon of mosquito breeding and dengue fever Methodology: This cross-sectonal study was conducted from January 2013 to December 2013 in two urban slums of Delhi, Balmiki Bast and Delhi Gate. All adults aged 20 years and above were included in the study irrespectve of sex and previous history of dengue. Knowledge, attude and practces against mosquito breeding were also taken through predesigned, pretested questonnaires. Results: A total of 49(20.5%) adults from Balmiki Bast and 190 from Delhi Gate were enrolled in the study. Mean IgG dengue OD levels of the study subjects was 1.62±0.568. Of the total, 86% were positve for dengue IgG positvity while 13% negatve and 1% equivocal. Of all partcipants, 214(89.9%) were aware of mode of dengue transmission while 25(10.1%) were not. Majority of the partcipants 137(57.3%) used liquid vaporizers for preventon of mosquito bites. Discussion: The current study reported that 85.4% of the healthy populaton in urban slums of Delhi is seropositve for dengue IgG, which indicates the unprecedented extent of exposure to dengue virus. It is 7.8% higher than the study conducted in Delhi in 1998(77.6%). It coincides with the rising trend of dengue cases every year in Delhi, making it an endemic region now. Keywords: Dengue, Sero-prevalence, IgG antbody, Sero-epidemiology Introducton Dengue has become one of the most important vector borne diseases over the decades with a steady rise of global incidence, increasing geographic distributon and a transiton from epidemic transmission with long inter-epidemic intervals to endemic with seasonal fuctuaton. 1 WHO currently estmates there may be 50–100 million dengue infectons every 1 III rd Year Post Graduate, 2,4 Director Professor, Department of Community Medicine. 3 Director Professor, Department of Microbiology. Correspondence: Dr. Shantanu Sharma, Department of Community Medicine. E-mail Id: shantanusharma145@gmail.com Orcid Id: htp://orcid.org/0000-0002-5064-4782 How to cite this artcle: Sharma S, Gupta VK, Chakravarty A et al. Dengue Sero-surveillance in Delhi: A Community-Based Study. J Commun Dis 2017; 49(4): 23-31. Digital Object Identfer (DOI): htps://doi.org/10.24321/0019.5138.201731 ISSN: 0019-5138