How to Cite: Kumar, V. S., Ahmed, N., Alphonso, J. K., Chandrasekar, S., & Boopathy, U. (2022). A review on pharmacological activities of Mukia maderaspatana. International Journal of Health Sciences, 6(S3), 4449–4459. https://doi.org/10.53730/ijhs.v6nS3.6826 International Journal of Health Sciences ISSN 2550-6978 E-ISSN 2550-696X © 2022. Manuscript submitted: 27 Dec 2021, Manuscript revised: 09 March 2022, Accepted for publication: 18 April 2022 4449 A review on pharmacological activities of Mukia maderaspatana Vasantha Kumar S. Department of Biochemistry, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai-600117, Tamil Nadu, India Navaith Ahmed Department of Biochemistry, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai-600117, Tamil Nadu, India John Alphonso K. Department of Biochemistry, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai-600117, Tamil Nadu, India Shobana Chandrasekar Department of Biochemistry, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai-600117, Tamil Nadu, India Usharani Boopathy Department of Biochemistry, Vels Institute of Science, Technology and Advanced Studies, Pallavaram, Chennai-600117, Tamil Nadu, India Email: raniushab1@gmail.comy Abstract---Cucurbits are consumable crops, belonging to the family of Cucurbitaceae. They are widely distributed in the regions of tropical and sub-tropical region. These tendril climbers are grown in village surrounding. The plant has been grown from olden days for its medicinal value. It is used as herbal drug for cough and cold. All parts of plant such as leaf, stem, root, fruit and seeds are used in historical system of medicine. Cucurbits are naturally trailing plant. Edible food such as watermelon and cucumber are found in cucurbit family. Plants belonging to cucurbits family are higher in nutritional value. Mukia maderaspatana belongs to Cucurbitaceae genus. It is (called as “musumusukkai” in tamil). It is also known as Cucumis maderaspatana. Mukia maderaspatana has pharmacological activities such as aperient, diuretic, stomachic, antipyretic, anti-flatulent, anti- asthmatic, antitussive, antihistaminic, antibronchitic, hypolipidemic, hepatoprotective, hypoglycaemic, antiulcer. Phytochemical screening shows the presence of glycosides, flavonoids, phenols, alkaloids, saponin, carbohydrate and steroid in ethanol and methanol