Research Article Seroprevalence of Hepatitis B Virus and Associated Factors among Health Professionals in University of Gondar Hospital, Northwest Ethiopia Aynishet Adane Gebremariam , 1 Adino Tesfahun Tsegaye , 2 Yalelet Fentaw Shiferaw, 3 Mebratu Mitiku Reta , 1 and Alem Getaneh 4 1 Department of Internal Medicine, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia 2 Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia 3 University of Gondar Comprehensive Specialized Hospital, Gondar, Ethiopia 4 Department of Medical Microbiology, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia Correspondence should be addressed to Aynishet Adane Gebremariam; ayne.2003@yahoo.com Received 3 September 2018; Revised 10 December 2018; Accepted 23 December 2018; Published 3 March 2019 Academic Editor: Gerardo E. Guill´ en Nieto Copyright © 2019 Aynishet Adane Gebremariam et al. Tis is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Introduction. Hepatitis B virus infection is one of the commonest occupational risks in healthcare workers. However; there is limited evidence regarding the prevalence of hepatitis in health professionals in Ethiopia. Objective. Tis study was aimed at assessing the prevalence of hepatitis B and associated factors in health professionals. Methods. Institution based cross-sectional study was conducted among health professionals at University of Gondar Hospital from January to February, 2015. Self-administered questionnaire was used to collect sociodemographic variables and blood sample was also taken to determine hepatitis B virus sero- status. Chi square test with 95% confdence interval (CI) was computed to assess the associations of diferent factors with hepatitis B infection. Result. A total of 332 health professionals (with a response rate of 92.2%) participated in the study. Most (98.5%) of health professionals were not vaccinated for hepatitis B. Te prevalence of hepatitis B in health professionals at UOG hospital was found to be 4.52% (95% CI: 2.4, 6.5). Hepatitis B infection was more common among males (P value =0.0299). Conclusion. Te prevalence of hepatitis B in health professionals in this study was comparable with other studies done in Ethiopia among health professionals. Males were more afected than females for hepatitis B infection. Hepatitis B virus vaccine, treatment for the infected, and training on infection prevention should be more available for healthcare workers. 1. Introduction Hepatitis B virus (HBV) is a small double-stranded DNA virus which predominantly afects the liver. It is a global public health problem accounting for more than 300 million HBV carriers worldwide and is found to be high in the developing countries particularly in Asia and Sub-Saharan Africa with a prevalence rate of 10-20%. HBV is one of the most common causes of acute and chronic liver disease [1]. Diferent community-based studies conducted in Ethiopia showed that the prevalence of hepatitis B seropositivity (HBsAg) ranges from 5 to 11% [2–7]. Although the modes of transmission of HBV vary in diferent geographical areas, the main routes of transmission are sexual intercourse, parenteral contact, and vertical transmission [8]. A study done in Ethiopia showed that the predominant modes of HBV transmission were found to be horizontal intrafamilial spread, harm full traditional practices, and use of unsterile materials [9]. HBV is one of the most commonly transmitted blood- borne viral infections in healthcare settings; hence it is the leading issue of concern particularly in resource-limited Hindawi Advances in Preventive Medicine Volume 2019, Article ID 7136763, 5 pages https://doi.org/10.1155/2019/7136763