Case Report MedInform DOI: 10.18044/MEDINFORM.202181.1292 ISSUE 1, 2021 1292 MedInform Regenerative endodontic procedure of permanent teeth with incomplete root development after application of a devitalizing agent – a case report Krasimir Hristov Department of Pediatric Dentistry, Faculty of Dental Medicine, Medical University of Sofia, Bulgaria Abstract In the recent years, there is a common belief that regenerative endodontics can provide high success rate in the treatment of permanent teeth with incomplete root development and in general to improve their long-term prognosis. New protocols are constantly being explored to improve the chances of a successful healing process. This case report demonstrates the effectiveness of the protocol in the treatment of fractured maxillary central incisors with incomplete root development and necrotic pulp and previous treatment of the pulp with devitalizing agent. It uses 2.5% hypochlorite, EDTA and saline for irrigation. The most distinctive feature is the use of minimal mechanical preparation of the channel walls with XP-Endo Finisher for 1 min. Clinical follow-up at 24 months showed fully functional asymptomatic teeth with completely formed root walls and closure of the apex. Keywords: regenerative endodontic procedure, XP- Endo Finisher, immature permanent teeth