DOI: 10.14260/jemds/2015/1140 ORIGINAL ARTICLE J of Evolution of Med and Dent Sci/ eISSN- 2278-4802, pISSN- 2278-4748/ Vol. 4/ Issue 45/ June 04, 2015 Page 7833 INCIDENCE OF CME AS MEASURED BY SPECTRAL DOMAIN OCT (SD-OCT) FOLLOWING EXTRA CAPSULAR CATARACT EXTRACTION (ECCE) Dhwani Garg 1 , Neelima Mehrotra 2 , Arvind Ram 3 , B. D. Sharma 4 , Akhil Agarwal 5 , Kapil Chopra 6 , Shikha Nailwal 7 HOW TO CITE THIS ARTICLE: Dhwani Garg, Neelima Mehrotra, Arvind Ram, B. D. Sharma, Akhil Agarwal, Kapil Chopra, Shikha Nailwal. “Incidence of Cme as Measured by Spectral Domain Oct (SD-OCT) Following Extra Capsular Cataract Extraction (ECCE).” Journal of Evolution of Medical and Dental Sciences 2015; Vol. 4, Issue 45, June 04; Page: 7833-7838, DOI:10.14260/jemds/2015/1140 ABSTRACT: AIM: To determine incidence of CME as measured by Spectral Domain OCT (SD-OCT) following extra capsular cataract extraction surgery by different techniques and to study tomographic characteristics of CME. MATERIALS AND METHODS: A prospective observational study to determine incidence of CME after ECCE by SD-OCT was carried out from June 2013 – May 2014. A total 102 eyes of patients following ECCE were included in the study and OCT was done preoperatively and at 2, 6 and 10 weeks after surgery. RESULTS: 2 eyes developed CME after 6 weeks of cataract surgery and there was a proportionate increase in macular thickness in all of these eyes postoperatively. CONCLUSION: Our data indicate that the onset of CME is rare after ECCE but with respect to preoperative values we observed an asymptomatic increase in macular thickness and volume at 6 weeks. KEYWORDS: CME-Cystoid Macular Edema, OCT-Optical Coherence Tomography, ECCE- extra- capsular cataract extraction. INTRODUCTION: Cystoid macular edema (CME) is the formation of fluid-filled cystoid spaces between the outer plexiform and inner nuclear layers of the retina, resulting from disruption of the blood-retinal barrier. It is a common complication observed after cataract surgery. Although the pathogenesis is still not fully understood, the diagnosis is usually easily missed clinically and confirmed by angiographic examination or recently by OCT. With modern surgical techniques the incidence of CME has decreased to 1% 1,2 The incidence of angiographic CME, without clinical macular edema, has been reported to be around 10–20% following cataract surgery. While it usually occurs 4– 12 weeks following surgery; there are a few cases reported after many months or years after the surgery 3 Optical coherence tomography (OCT) is a noninvasive and quantitative imaging modality, which provides cross-sectional images of the retina, with the help of ~800 nm diode laser light. 4-7 The anatomic findings of cystoid macular edema demonstrated by spectral-domain OCT are described by their degree of reflectivity. Hypo-reflective areas in an OCT retinal image usually represent areas of extracellular fluid found in cystoid macular edema. AIM AND OBJECTIVES: 1. To determine incidence of CME post ECCE by SD-OCT. 2. To study macular thickness changes after cataract surgery. MATERIALS AND METHODS: Patients with senile cataracts, who underwent ECCE by different techniques with IOL implantation, were taken in the study.