Case Report
Left Vocal Cord Paralysis Detected by PET/CT in
a Case of Lung Cancer
Ali Ozan Oner,
1
Adil Boz,
2
Evrim Surer Budak,
3
and Gulnihal Hale Kaplan Kurt
4
1
Nuclear Medicine Department, School of Medicine, Afyon Kocatepe University, 03200 Afyon, Turkey
2
Nuclear Medicine Department, School of Medicine, Akdeniz University, 07070 Antalya, Turkey
3
Nuclear Medicine Department, Antalya Training and Research Hospital, Antalya, Turkey
4
Nuclear Medicine Department, Isparta State Hospital, Isparta, Turkey
Correspondence should be addressed to Adil Boz; boz@akdeniz.edu.tr
Received 6 September 2015; Accepted 18 October 2015
Academic Editor: Jose I. Mayordomo
Copyright © 2015 Ali Ozan Oner et al. Tis is an open access article distributed under the Creative Commons Attribution License,
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
We report a patient with lung cancer. Te frst PET/CT imaging revealed hypermetabolic mass in the lef aortopulmonary region and
hypermetabolic nodule in the anterior segment of the upper lobe of the lef lung. Afer completing chemotherapy and radiotherapy
against the primary mass in the lef lung, the patient underwent a second PET/CT examination for evaluation of treatment response.
Tis test demonstrated, compared with the frst PET/CT, an increase in the size and metabolic activity of the primary mass in the
lef lung in addition to multiple, pathologic-sized, hypermetabolic metastatic lymph nodes as well as multiple metastatic sclerotic
areas in bones. Tese fndings were interpreted as progressive disease. In addition, an asymmetrical FDG uptake was noticed at the
level of right vocal cord. During follow-up, a laryngoscopy was performed, which demonstrated lef vocal cord paralysis with no
apparent mass. Tus, we attributed the paralytic appearance of the lef vocal cord to infltration of the lef recurrent laryngeal nerve
by the primary mass located in the apical region of the lef lung. In conclusion, the knowledge of this pitfall is important to avoid
false-positive PET results.
1. Introduction
Vocal cord paralysis occurs due to pathologies of the nerves
that innervate vocal cords. Te nerves that make vocal cords
vibrate consist of neurons originating from the region of
nucleus ambiguus in the brainstem. Te nerve arising from
the nucleus is called the “vagus nerve,” which is the thickest
nerve in the human body and extends to thoracic and
abdominal cavities [1]. Te nerve gives of 2 thin branches
for larynx at the base of the skull. Te frst one is called the
“superior laryngeal nerve” and the second one is called the
“recurrent laryngeal nerve (RLN).” Te latter conveys orders
to both opening and closure muscles. Te problems in that
nerve cause paralysis of both opening and closure muscles,
leading to loss of their basic functions. Hence, respiratory
difculty and hoarseness and aspiration problems due to
failure of closure arise. Problems of superior laryngeal nerve,
on the other hand, become manifest, with a monotonous, thin
voice as well as difculty in tone control and singing songs.
Causes of Vocal Cord Paralysis:
(i) Idiopathic diseases.
(ii) Viral neuritis.
(iii) Masses, tumors compressing vocal nerves in brain,
base of the skull, neck, thyroid region, and thoracic
cavity.
(iv) Surgical interventions (especially thyroid surgery).
(v) Being secondary to intubation in certain surgical
operations [1].
18
F-fuorodeoxyglucose positron emission tomography/
computed tomography (
18
FDG-PET/CT) scans are utilized
for identifcation of stage cancers clinically but the causes
of false-positive and false-negative results must be identi-
fed to evaluate the results of the test. As a result of the
increased glucose consumption, FDG accumulates in benign
and malignant conditions. Te degree of muscle work is
Hindawi Publishing Corporation
Case Reports in Oncological Medicine
Volume 2015, Article ID 617294, 4 pages
http://dx.doi.org/10.1155/2015/617294