International Journal of Health Sciences & Research (www.ijhsr.org) 733 Vol.5; Issue: 6; June 2015 International Journal of Health Sciences and Research www.ijhsr.org ISSN: 2249-9571 Case Report Solitary Eruptive Vellus Hair Cyst In An Adult- An Unusual Presentation: Case Report With A Brief Review Of Literature Swati Sharma 1* , Ashish Gupta 2** , Padmapriya Jaiprakash 1* 1 Associate Professor, 2 Clinical Fellow * Department of Pathology, ** Department of Medical Genetics, Kasturba Medical College, Manipal University, Manipal, Karnataka, India Corresponding Author: Swati Sharma Received: 24/04/2015 Revised: 15/05/2015 Accepted: 22/05/2015 ABSTRACT Eruptive vellus hair cysts are a type of cutaneous cysts of skin appendages usually seen in children and teenagers. We report a case of solitary eruptive vellus hair cyst on the thigh in a 38 year old lady which clinically mimicked sebaceous cyst. Diagnosis was confirmed on histopathology. Key words: cutaneous cyst, infundibular, papule, vellus hair. INTRODUCTION Eruptive vellus hair cysts (EVHC) are a type of relatively uncommon cutaneous cysts of skin appendages. [1] Precise etiopathogenesis is yet to be established, although few possible mechanisms have been described in literature. These benign lesions usually present with multiple small asymptomatic papules. Nearly 25 percent of the cases have spontaneous resolution [2] On histology, EVHCs are characteristically located in the mid dermis and contain variable amount of laminated keratin and multiple transversally and obliquely cut vellus hair [3] We report a case of EVHC in an adult female presenting unusually as solitary asymptomatic nodule on the right thigh. We also emphasize on the precise diagnosis of this relatively uncommon and frequently unrecognized lesion of vellus hair follicles. CASE REPORT A 38 year old female came to the Surgery outpatient department with nodule over the right thigh since 3 years. There was no associated pain, fever, redness or any other similar swelling or nodule in the body. She gives history of surgery at the same site around 8 years back, details for which are not available. Patient had been diagnosed with fibroadenoma in the left breast recently. There was no other significant family or personal history. On examination, a cystic nodule was identified on the right thigh measuring 1x 1cm. The cystic mass was excised and sent for histopathology with clinical suspicion of sebaceous cyst. Grossly, skin covered fibrous tissue measuring 2.5x2x1.8 cm was received. Cut section showed grey yellow areas. No cyst was identified. On microscopy, sections