Open Access Library Journal 2021, Volume 8, e7982 ISSN Online: 2333-9721 ISSN Print: 2333-9705 DOI: 10.4236/oalib.1107982 Dec. 15, 2021 1 Open Access Library Journal Does the Location and Prevelance of Gastric Intestinal Metaplasia Change in Patients with Functional Dyspepsia Tahir Buran 1* , Elmas Kasap 1 , Semin Ayhan 2 1 Department of Gastroenterology, Manisa Celal Bayar University Faculty of Medicine, Manisa, Turkey 2 Department of Pathology, Manisa Celal Bayar University Faculty of Medicine, Manisa, Turkey Abstract Gastric intestinal metaplasia plays a significant role in the pathogenesis of in- testinal gastric cancer. Objective: A retrospective analysis of demographic characteristics, site of involvement, and incidence was performed involving patients who underwent endoscopy who had biopsy-diagnosed intestinal me- taplasia. Materials and Methods: The study included 720 patients with func- tional dyspepsia retrospectively from among 6160 patients who underwent upper endoscopy in Celal Bayar University, Faculty of Medicine, Gastroenter- ology Department, between 2014 and 2020. Results: Intestinal metaplasia was detected at the antrum, corpus, and angulus in 59.94%, 13.47%, and 28.57% of the cases, respectively. Antral lesions were significantly more prevalent (P < 0.05). Of the patients with IM, 63.5% had HP positivity, with a significant as- sociation between IM positivity and HP positivity (P < 0.05). There was a sig- nificant difference between patients with or without a history of chronic PPI use in terms of the prevalence of intestinal metaplasia (P < 0.05). Conclusion: These results suggest that the endoscopic follow-up of patients with IM re- quires additional attention to the lesser curvature of the antrum as well as the gastric angulus. Subject Areas Biochemistry Keywords Gastric İntestinal Metaplasia, Helicobacter Pylori, Gastritis, Functional Dispepsia How to cite this paper: Buran, T., Kasap, E. and Ayhan, S. (2021) Does the Location and Prevelance of Gastric Intestinal Meta- plasia Change in Patients with Functional Dyspepsia. Open Access Library Journal, 8: e7982. https://doi.org/10.4236/oalib.1107982 Received: September 19, 2021 Accepted: December 12, 2021 Published: December 15, 2021 Copyright © 2021 by author(s) and Open Access Library Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/ Open Access