Neto, et al., J Pain Relief 2015, 4:6
DOI: 10.4172/2167-0846.1000205
Case Report Open Access
Volume 4 • Issue 6 • 1000205
J Pain Relief
ISSN: 2167-0846 JPAR an open access journal
Glossopharyngeal Neuralgia: Case Report
Sergio Neto
1,*
, Kleber Duarte
2
, Guilherme Alves Lepski
2
, Leonardo Moura
1
, Nilton Caetano da Rosa
3
and Manoel Jacobsen Teixeira
1,2
1
Division of Neurosurgery, University of Sao Paulo School of Medicine, Sao Paulo, Brazil
2
Division Functional Neurosurgery, University of São Paulo School of Medicine, São Paulo, Brazil
3
Division of Surgical Oncology, International Research Center, A.C. Camargo Cancer Center, São Paulo, Brazil
Abstract
Glossopharyngeal neuralgia (GPN) is an unusual cause of facial pain, corresponding to approximately 0.2-1.3%.
Patients usually presents with facial pain associated with daily life activities (cough, swallow) and in severe cases
with syncop. Epidemiology of the pathology demonstrates controversy about the predominance of the male, being
consensus from patients over 50 years. We present a case report of a 51 patient diagnosed and treats for this rare
disease with good outcome.
Keywords: Glossopharyngeal neuralgia; Pain; Headache
Abbreviations: GPN: Glossopharyngeal Neuralgia; GKS: Gamma
Knife Surgery; MRI: Magnetic Ressonance Imaging; CT: Computarized
Tomography
Introduction
Glossopharyngeal neuralgia (GPN) is an unusual cause of facial pain,
corresponding to approximately 0.2-1.3% of patients with facial pain
[1]. Te frst clinical description was assigned to weisenberg 1910 [2].
Te practice of patients is usually sudden afecting the glossopharyngeal
nerve path, characterized by pain triggered by swallowing, chewing,
coughing, talking, and may or not be associated with syncop frames/
cardiorespiratory stop in rare cases [3,4]. Te clinical or surgical
treatment options may include the use of anticonvulsants and in severe
or selected cases neurovascular decompression or Gamma Knife
surgery [5-8].
Case Report
51-year-old male with pain in shock of sudden onset is 8 months
of pain in neck region with irradiation to the region of hemiface
right to Franca worsens when swallowing and chewing. Sick said
several paroxysms, having 1 frequency crisis every 3 days. Afer
investigation in another service with trigeminal neuralgia, chance of
requested the evaluation team. In the frst assessment the patient was
in use of Gabapentin 900 mg/d with inadequate control of paroxysms.
Neurological examination: alert and oriented gear without changes and
without strength defcits and/or sensitivity of note the same featured
pain swallowing and spontaneous cough. Right Gag Refex abolished
without deviation of the uvula. Magnetic resonance imaging illustrated
a great right neurovascular confict between posteroinferior Cerebellar
artery with glossopharyngeal nerve (Figures 1 and 2).
Te patient underwent a retrossigmoid craniotomy and
neurovascular decompression of glossopharyngeal nerve, having in
the frst post-operative presented fully symptomatic improvement,
having received high in the 4th post-operative without complaints and
medications until 1st year outpatient follow up.
Discussion
Glossopharyngeal neuralgia (GPN) is an unusual cause of facial
pain, corresponding to approximately 0.2-1.3% of patients with facial
pain or a hundred times less frequent when compared with trigeminal
neuralgia [1].
Te frst description of the clinic was assigned to Weisenberg 1910
in a patient with pontocerebelar angle tumor diagnosis and Harris in
1926 the name of glossopharyngeal neuralgia [2,9]
Figure 1(A): MRI T2seq. FIESTA: Right vascular compression/Confict.
*Corresponding author: Neto S, Division of Neurosurgery, University of
Sao Paulo School of Medicine. Sao Paulo, Brazil. Address: Dr. Enéas de
Carvalho Aguiar Street, 255-5th Floor, Zipcode: 05403-000-São Paulo.
Brazil, Tel: 55 11 3091-3116; E-mail: sgsnnc@gmail.com
Received August 18, 2015; Accepted October 27, 2015; Published October 30,
2015
Citation: Neto S, Duarte K, Lepski GA, Moura L, da Rosa NC, et al.
(2015) Glossopharyngeal Neuralgia: Case Report. J Pain Relief 4: 205.
doi:10.4172/21670846.1000205
Copyright: © 2015 Neto S, et al. This is an open-access article distributed under
the terms of the Creative Commons Attribution License, which permits unrestricted
use, distribution, and reproduction in any medium, provided the original author and
source are credited.
Te etiology of trigeminal neuralgia in most cases is primary/
idiopathic or secondary to neurovascular compression (posteroinferior
Cerebellar arteries or branches of verteral arteries), skull base tumors
or cerebellar point angle tumors [10]. Epidemiology of the pathology
demonstrates controversy about the predominance of the male, being
consensus from patients over 50 years [10].
Te clinic of patients is usually sudden afecting the glossopharyngeal
nerve path, characterized by pain (unilateral electric shock type,
abrupt, and located in the ear, at the base of the tongue, tonsillar fossa,
or under the angle of the mandible) triggered by swallowing, chewing,
coughing, talking, and may or not be associated with sincopais frames/
cardiorespiratory stop in rare cases [3,4]
Te investigation of patients with neuralgia includes realization of
head CT and/or Brain MRI in order to highlight tumors or vascular
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ISSN: 2167-0846