European Heart Journal: Acute Cardiovascular Care
2016, Vol. 5(5) 461–467
© The European Society of Cardiology 2016
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DOI: 10.1177/2048872616647708
acc.sagepub.com
EUROPEAN
SOCIETY OF
CARDIOLOGY
®
Mode of admission and its effect on
adherence to reperfusion therapy
guidelines in Belgian STEMI patients
Céline Rousseaux
1
, Pierre Mols
2,3
, Peter R Sinnaeve
4
,
Carl Convens
5
, Philippe Dubois
6
, Pascal Vranckx
7
, Sofie Gevaert
8
,
Patrick Coussement
9
, Ahmed SE Ramadan
2
,
Christophe Beauloye
10
, Marc Renard
3
, Patrick Evrard
11
,
Jean-François Argacha
12
, Herbert De Raedt
13
,
Kristien Wouters
14
and Marc J Claeys
15
Abstract
Objectives: Emergency medical services play a key role in the recognition and treatment of ST-segment elevation
myocardial infarction (STEMI). This study evaluates the effect of emergency medical services use on adherence to
reperfusion therapy guidelines in Belgian STEMI patients and on in-hospital mortality.
Methods: The mode of admission with against without emergency medical services was associated with baseline risk
profile, reperfusion modalities and in-hospital mortality in 5692 consecutive STEMI patients from 2012 to 2014.
Results: A total of 3896 STEMI patients (68%) were transported to the hospital by emergency medical services, and
1796 patients (32%) arrived at the hospital using their own transport (self-referral). Emergency medical services patients
were older than self-referral patients (64 vs. 62 years) and more frequently presented with cardiac arrest (14% vs. 5%)
and with cardiogenic shock (10% vs. 4%). Emergency medical services patients received primary percutaneous coronary
intervention more often (95% vs. 91%, P<0.0001) and more frequently within 90 minutes (72% vs. 65%, P<0.001).
Moreover, the time interval between symptom onset and reperfusion therapy was shorter in the emergency medical
services group (median of 195 vs. 255 minutes, P<0.001). Crude in-hospital mortality was higher in the emergency
medical services group (7.7% vs. 3.8%, P<0.0001) and was mainly driven by the high prevalence of cardiogenic shock
and cardiac arrest in the emergency medical services group. After adjustment, the impact on mortality was no longer
significantly different.
Conclusion: Emergency medical services are used by two-thirds of Belgian STEMI patients and are associated with
a better adherence to STEMI reperfusion guidelines. These data favour the use of emergency medical services as the
preferred transfer system for patients with chest pain suspicious for STEMI.
Keywords
Emergency medical services, STEMI, reperfusion therapy
Date received: 14 August 2015; accepted: 29 March 2016
1
Hôpital Molière et Ixelles, Emergency Department, Brussels, Belgium
2
CHU Saint-Pierre, Emergency Department, Belgium
3
ULB Brussels, Department of Cardiology, Belgium
4
UZ Leuven, Department of Cardiology, Belgium
5
ZNA Antwerpen, Department of Cardiology, Belgium
6
CHU Charleroi, Department of Cardiology, Belgium
7
Virga Jesse Hasselt, Department of Cardiology, Belgium
8
UZ Gent, Department of Cardiology, Belgium
9
AZ Brugge, Department of Cardiology, Belgium
10
UCL Louvain, Department of Cardiology, Belgium
647708ACC 0 0 10.1177/2048872616647708European Heart Journal: Acute Cardiovascular CareRousseaux et al.
research-article 2016
Original scientific paper
11
UCL Mont-Godinne, Department of Intensive Care, Belgium
12
UZ Brussels, Department of Cardiology, Belgium
13
OLV Aalst, Department of Cardiology, Belgium
14
University Hospital Antwerp, Department of Statistics, Belgium
15
University Hospital Antwerp, Department of Cardiology, Belgium
Corresponding author:
Marc J Claeys, University Hospital Antwerp, Wilrijkstraat 10, 2650
Edegem, Belgium.
Email: marc.claeys@uantwerpen.be
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