SHORT COMMUNICATION Increasing Frequency of Seborrheic Keratosis Diagnoses as a Favorable Consequence of Teledermatology-Based Skin Cancer Screening: A Cross-sectional Study of 34,553 Patients David Moreno-Ramı ´rez 1 • Jesu ´ s Raya-Maldonado 1 • Macarena Morales-Conde 1 • Teresa Ojeda-Vila 1 • Francisco J. Martı ´n-Gutie ´rrez 1 • Andre ´s Ruı ´z-de-Casas 1 • Almudena Ferna ´ndez-Orland 1 • Herrerı ´as-Esteban JM 2 • Lara Ferra ´ndiz 1 Ó Springer International Publishing Switzerland 2017 Abstract Background Screening of skin cancer by teledermatology (TD) has improved the early detection of skin cancer by enhancing access to skin cancer clinics. Objective We sought to analyze how TD-based skin can- cer screening has changed the frequency of consultations for benign lesions. Patients and methods A cross-sectional study including teleconsultations received during a 7-year period was conducted to analyze and compare the trendlines of each lesion type over the study period. Trendlines were analyzed using a linear regression model with the R-squared (R 2 ) test for goodness of fit. Results A total of 34,553 teleconsultations were included in the study. Seborrheic keratoses, followed by benign melanocytic lesions, were the most frequent lesions diag- nosed. The pick-up rate for malignant lesions was 1:8.6 teleconsultations. Seborrheic keratoses and precancerous lesions showed a positive trendline with good fit to the linear model (R 2 = 0.8 and R 2 = 0.8, respectively). Tis-T1 malignant melanoma (in situ melanoma or melanoma with a Breslow thickness \ 1 mm) showed an increasing trend- line with moderate-to-low fit to the model (R 2 = 0.4). Conclusions TD-based screening of skin cancer is associ- ated with an increasing rate of consultations involving seborrheic keratoses, which can be considered a consequence of improved access to dermatologists result- ing from TD implementation. Key Points It is currently unknown how routine skin cancer screening changes the frequency of the lesions consulted. The present analysis found that teledermatology- based skin cancer screening is associated with an increasing frequency of seborrheic keratoses. Our results support the hypothesis that the larger the number of patients seeking care for benign lesions the greater the likelihood of identifying skin cancer at an earlier stage. 1 Introduction Screening of skin cancer patients by teledermatology (TD) has been shown to improve the early detection of skin cancer by increasing accessibility to skin cancer clinics [1]. A significant shortening of wait times as well as better resource allocation for patients with skin cancer (e.g., in- person skin cancer clinics, surgical rooms for patients with lesions appropriate for surgery) are readily guaranteed with TD use. The initial prognosis of malignant melanoma (MM) has also been improved as a consequence of the remote screening provided by TD [2]. Patients who might never have sought dermatological care are now receiving early diagnoses of skin cancer or & David Moreno-Ramı ´rez dmoreno@e-derma.org 1 Chief of the Medical and Surgical Dermatology Unit, HUVM Teledermatology Network, Hospital Universitario Virgen Macarena, Avda. Dr. Fedriani s/n, 41009 Seville, Spain 2 ICT Department, Hospital Universitario Virgen Macarena, Seville, Spain Am J Clin Dermatol DOI 10.1007/s40257-017-0283-z