Reprod Dom Anim 2016; 1–4 wileyonlinelibrary.com/journal/rda
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1 © 2016 Blackwell Verlag GmbH
Received: 22 July 2016
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Accepted: 24 October 2016
DOI: 10.1111/rda.12899
Contents
This study compared endometrial cytology vis-a-vis uterine fuid cytology for assess-
ment of uterine health in clinically normal and subclinical endometrits (SE)-afected
bufaloes. Uterine fuid samples and endometrial samples were collected from the buf-
faloes (n = 38) at oestrus using blue sheath and cytobrush, respectvely. The smears
were stained with Field stain for 3 minutes, and a minimum of 400 cells were counted
in each smear for determinaton of the percentage of polymorphonuclear (PMN) leu-
cocyte. The incidence of subclinical endometrits, based on the cytobrush cytology,
was 23.08%. The correlaton between cytobrush cytology with uterine fuid cytology
was positve and signifcant(r = .37; p = .02). The rato of PMN leucocyte in cytobrush
cytology to uterine fuid cytology was 1:2.4. ROC analysis revealed that the threshold
value of 6.16% PMN leucocyte in uterine fuid cytology showed a diagnostc sensitv-
ity and specifcity of 100% in diferentatng normal from SE-afected bufaloes. In
conclusion, collecton of uterine fuid was easier compared to collecton of endome-
trial samples using cytobrush and the percentage of PMN leucocyte in uterine fuid
cytology can be used as a tool for diagnosis of subclinical endometrits in bufaloes.
Animal Reproducton Gynaecology &
Obstetrics, Natonal Dairy Research
Insttute, Karnal, Haryana, India
Correspondence
A Kumaresan, Animal Reproducton
Gynaecology & Obstetrics, Natonal Dairy
Research Insttute, Karnal, Haryana, India.
Emails: ogkumaresan@gmail.com;
A.Kumaresan@icar.gov.in
Funding informaton
ICAR-Natonal Dairy Research Insttute,
Karnal
SHORT COMMUNICATION
Efciency of uterine fuid cytology in the diagnosis of
subclinical endometrits in the water bufalo (Bubalus bubalis)
SC Gahlot | S Kumar | A Kumaresan | S Chand | RK Baithalu | S Lathika |
TK Patbandha | SS Lathwal | TK Mohanty
1 | INTRODUCTION
Post-partum uterine infecton is the most common cause of infer-
tlity in the catle and bufalo leading to delayed uterine involuton,
prolonged tme untl frst oestrus, increased number of services per
concepton and prolonged calving to concepton interval. Uterine in-
fectons are generally classifed as puerperal metrits, clinical metrits,
clinical endometrits, subclinical endometrits and pyometra (Sheldon,
Lewis, LeBlanc, & Gilbert, 2006). Subclinical endometrits (SE) is the
most prevalent of all uterine diseases; it afects ~ 30% of lactatng
dairy cows, with the prevalence ranging from 11 to >70% in some
herds (Barlund, Carruthers, Waldner, & Palmer, 2008; Galvão, Greco,
Vilela, SáFilho, & Santos, 2009; Gilbert, Shin, Guard, Erb, & Frajblat,
2005; Kasimanickam et al., 2004). The incidence of uterine infecton
was higher in bufalo than that of cow because bacterial contamina-
ton of the vagina and other external reproductve organs might occur
during wallowing (Azawi, 2010). The reported incidence of endome-
trits in the bufalo ranged from 20.0 to 47.9% (Ghanem, Shalaby,
Sharawy, & Saleh, 2002) with an adverse efect on the reproductve
performance (Azawi, 2008).
Among the several methods used for detecton of subclinical en-
dometrits, endometrial biopsy is considered as defnitve diagnosis
(Noakes, Parkinson, England, & Arthur, 2002) while endometrial cytol-
ogy is considered the reference method because of the repeatability
of the test (Barlund et al., 2008; Kasimanickam et al., 2005). However,
restlessness temperament and comparatvely thinner and coiled uterus
in bufaloes (Srivastava & Kumaresan, 2014; Srivastava, Kumaresan,
Mohanty, & Prasad, 2013) pose problems in using endometrial biopsy
and cytobrush techniques. Further, the availability of the cytobrush
designed for use in the bufalo is very much limited. Thus, evolving an
easy method for detecton of SE assumes signifcance in this species.
Personal experience of the authors indicate that collecton of uterine
fuid is easier in bufaloes compared to cytobrush technique because
the sheath used for collecton of uterine fuid does not require a phys-
ical contact with endometrial lining and thus less traumatzing and
less discomfort to the bufalo. With this backdrop, in this study, we