How to Cite: Aaghaz, S., Gupta, S., Alauddin, W., Bashir, M., & Bharti, I. (2022). A study of cardiac autonomic functions in patients with chronic migraine versus chronic Tension-type Headache (TTH) in adults cardiac autonomic functions in headache. International Journal of Health Sciences, 6(S1), 7003–7013. https://doi.org/10.53730/ijhs.v6nS1.6506 International Journal of Health Sciences ISSN 2550-6978 E-ISSN 2550-696X © 2022. Manuscript submitted: 18 Feb 2022, Manuscript revised: 09 March 2022, Accepted for publication: 27 April 2022 7003 A study of cardiac autonomic functions in patients with chronic migraine versus chronic Tension-type Headache (TTH) in adults cardiac autonomic functions in headache . Shams Aaghaz Post graduate student, Department of Physiology, VMMC & Safdarjung Hospital, New Delhi, India. Email: drshamsaaghaz@icloud.com Supriya Gupta Professor, Department of Physiology, VMMC & Safdarjung Hospital, New Delhi, India. Waqas Alauddin Assistant Professor, Department of Physiology, HBTMC & Dr. RN Cooper Hospital, Juhu, Mumbai, India. Email: dr.waqas7@gmail.com Musharaf Bashir Lecturer, Department of Physiology, GMC & SMHS hospital, Srinagar, J&K, India. Email: dr.musharaf.mb@gmail.com Imtiyaz Bharti Post Graduate student, Department of Physiology, VMMC & Safdarjung Hospital, New Delhi, India. Email: imtiyaz197981@gmail.com Abstract---Objective: To assess cardiac autonomic functions in patients with chronic migraine and chronic tension-type headache (TTH) in adults using heart rate variability (HRV). Methods: Two groups of patients having chronic migraine (n = 25) and chronic TTH (n = 25) were enrolled for this study. HRV was analyzed with the help of BIOPAC MP150. Statistical analysis was performed with SPSS version 21. Unpaired t-test and Mann-Whitney test were used for parameters with normal and nonnormal distribution, respectively. Results: In chronic migraine group, SDNN (38.90 ± 22.14 vs 41.71 ± 20.81 ms, p=1.000), RMSSD (39.20 ± 25.14 vs 64.11 ± 156.74 ms, p=0.437) and pNN50 (13.37 ± 17.94 vs 18.56 ± 20.42, p=0.496) were