This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1002/jgm.3160 This article is protected by copyright. All rights reserved. rajendran karthick (Orcid ID: 0000-0003-3938-3347) Association of Metabolic Syndrome and Patatin-like phospholipase 3 - rs738409 Gene variant in Non-alcoholic fatty liver disease among Chennai based South Indian population Short title: MetS and PNPLA3 gene variant in NAFLD Dr.KRISHNASAMY NARAYANASAMY 1*# D.M., Dr. RAJENDRAN KARTHICK 2*# Ph.D., Mrs. PRIYADARSHINI PANNEERSELVAM 3 M.Sc., Ms. NITHYA MOHAN 4 M.Sc., Dr. RAMACHANDRAN ARUNKUMAR 5 Ph.D., Dr. RADHIKA PRAKASH 6 D.M., Mr. RAJARAM MUTHUKUMARAN 7 M.BA. 1. Professor & Director, Institute of Hepatobiliary Sciences, Madras Medical College, Chennai – 600003, Tamil Nadu, India. Email ID: drkns_1963@yahoo.com, Phone No: +91 9841170145 2. Research Scientist II, Multidisciplinary Research Unit (MRU), Madras Medical College, Chennai - 600003, Tamil Nadu, India. Email ID: rkarthickphd@gmail.com, Phone No: +91 9790787578 3. Lab Technician, Multidisciplinary Research Unit (MRU), Madras Medical College, Chennai - 600003, Tamil Nadu, India. Email ID: priya_shini2008@yahoo.com, Phone No: +91 9841519849 4. Research Assistant (Project), Multidisciplinary Research Unit (MRU), Madras Medical College, Chennai - 600003, Tamil Nadu, India. Email ID: nithyamohan18@gmail.com, Phone No: +91 9655213526 5. Research Scientist I, Multidisciplinary Research Unit (MRU), Madras Medical College, Chennai - 600003, Tamil Nadu, India. Email ID: arunkumarunom@gmail.com, Phone No: +91 9840116781