This is an open-access article distributed under the term of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-sa/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work id properly credited 1 Journal of Agromedicine and Medical Sciences. 2022. 8(1): 1-5 JOURNAL OF AGROMEDICINE AND MEDICAL SCIENCES (AMS) ISSN : 2460-9048 (Print), ISSN : 2714-5654 (Electronic) Available online at http://jurnal.unej.ac.id/index.php/JAMS Laporan Kasus: Penatalaksanaan Otitis Media Supuratif Kronis Tipe Kolesteatoma dengan Komplikasi Abses Otak Berulang Management of Chronic Supurative Otitis Media Cholesteatoma Type with Recurrent Brain Abscess Complication: A Case Report Khairani Ayunanda Ikhlas 1*) , Yan Edward 1 1 Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine Andalas University / Dr. M. Djamil General Hospital Article Info Article History: Received: July 15, 2021 Accepted: January 10, 2022 Published: February 28, 2022 *)Corresponding author: E-mail: khairaniayunandaikhlas88@gmail.com How to cite this article: Ikhlas, K.A. dan Edward, Y., (2022). Management of Chronic Supurative Otitis Media Cholesteatoma Type with Recurrent Brain Abscess Complication: A Case Report. Journal of Agromedicine and Medical Sciences, 8(1), 1-5. https://doi.org/10.19184/ams.v8i1.2436 2 Abstrak Otitis media supuratif kronik didefinisikan sebagai suatu inflamasi kronis yang melibatkan suatu mukosa telinga tengah dan sel-sel mastoid. Abses otak merupakan komplikasi intrakranial kedua terbanyak akibat otitis media setelah meningitis. Pemberian antibiotik hanya efektif pada fase awal terbentuknya abses otak, sehingga diperlukan tatalaksana bedah jika kapsul abses sudah terbentuk. Dilaporkan satu kasus seorang pasien laki-laki usia 22 tahun dengan diagnosis otitis media supuratif kronis auris dekstra tipe kolesteatom dengan komplikasi abses serebri berukuran 7x5x5 cm. Terapi antibiotik empiris diberikan pada pasien dilanjutkan dengan tatalaksana drainase abses serebri, namun terjadi pembentukan abses serebri berulang. Kemudian, dilakukan tindakan drainase abses serebri kedua diikuti dengan tindakan timpanomastoidektomi dinding runtuh auris dekstra. Sebagai kesimpulan, otitis media supuratif kronis dengan komplikasi abses serebri ditatalaksana dengan drainase abses jika ukuran abses >2 cm dan diikuti dengan timpanomastoidektomi dinding runtuh. Abses otak otogenik dapat terjadi berulang apabila terapi antibiotik yang diberikan tidak adekuat terkait kapsul abses yang sudah terbentuk. Kata kunci : abses otak otogenik, timpanomastoidektomi, OMSKotitis media supuratif kronis, drainase Abstract Chronic suppurative otitis media is defined as a chronic inflammation involving a middle ear mucosa and mastoid cells. Brain abscess is the second most common intracranial complication of otitis media after meningitis. Antibiotics are only effective in the early stages of brain abscess formation, so surgical treatment is needed if the abscess capsule has formed. We report a case of a male patient aged 22 years with a diagnosis of chronic suppurative otitis media auris dextra cholesteatoma type with complications of cerebral abscess measuring 7x5x5 cm. Empirical antibiotic therapy was given to the patient followed by management of cerebral abscess drainage, but recurrent cerebral abscess formation occurred. Then, drainage of the second cerebral abscess was performed followed by tympanomastoidectomy canal wall down for right auricle. In conclusion, chronic suppurative otitis media complicated by cerebral abscess was managed by drainage of the abscess if the abscess size was >2 cm and followed by tympanomastoidectomy canal wall down. Otogenic brain abscess can recur if the antibiotic therapy given is inadequate due to abscess capsule that has formed. Keywords: otogenic brain abscess, tympanomastoidectomy, CSOM,drainage