Contact Dermatitis • Contact Points FIRST CASE OF CONTACT DERMATITIS CAUSED BY HYDROXYPROPYL TETRAHYDROPYRANTRIOL • ASSIER ET AL. First case of contact dermatitis caused by hydroxypropyl tetrahydropyrantriol used in an anti-ageing cream Haudrey Assier 1 , Pierre Wolkenstein 1,2 and Olivier Chosidow 1,2 1 Department of Dermatology, AP-HP, Hôpital Henri-Mondor, 94010 Créteil, France and 2 Department of Dermatology, Assistance Publique–Hôpitaux de Paris, Hôpital Henri-Mondor, Université Paris est Créteil Val de Marne et Centre d’Investigation Clinique (CIC) 006, 94010 Créteil, France doi:10.1111/cod.12756 Key words: allergic contact dermatitis; case report; hydroxypropyl tetrahydropyrantriol (CAS no. 439685-79-7); Pro-xylane. Hydroxypropyl tetrahydropyrantriol (Pro-Xylane ™ ) has been widely used in cosmetics since 2006 as a ‘natural’ anti-ageing agent derived from beech wood. We report the frst case of contact dermatitis induced by hydroxypropyl tetrahydropyrantriol. Correspondence: Haudrey Assier, Department of Dermatology, Hôpital Henri-Mondor, 51 avenue du Maréchal de Lattre de Tassigny, 94010 Créteil Cedex, France. Tel: +33 149 815 501; Fax: +33 149 812 508. E-mail: haudrey.assier@hmn.aphp.fr Conflicts of interest: The authors declare no conflict of interests. Financial disclosure: None. Case Report A 65-year-old woman was referred to us for two episodes of eyelid contact dermatitis related to anti-ageing creams: Revitalift ® (L’Oreal, Paris, France) and Néovadiol ® © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd 60 Contact Dermatitis, 77, 49–63