Case Report MedInform ISSUE 2, 2018 846 MedInform Patient with osteoarthritis, aggravated by focal infection from dental origin-a case report Assya Krasteva 1 , Yanitsa Istatkova 1 , Mirela Marinova-Takorova 2 1. Department of Oral Imaging and Oral Diagnostics, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria 2. Department of Conservative Dentistry, Faculty of Dental Medicine, Medical University – Sofia, Bulgaria; Abstract Osteoarthritis is a degenerative joint disease, affecting approximately 27 million Americans. It can affect any joint, but it occurs most often in knees, hips, lower back and neck, small joints of the fingers and the bases of the thumb and big toe. We present a 53 years-old woman with chronic OA of the small joints of the fingers with complaints of pain, swollen and warmed joints of the left and right hands. The patient was referred to the Department of Oral Imaging and Oral Diagnostics to perform a consultation due to elevated levels of CRP and ESR. The patient underwent focal dental diagnostic protocol. We remarked an active dental focus- tooth 46. It was retreated endodontically under antibiotic protection and the patient was followed-up after one month with decreased levels of CRP and ESR. Keywords: osteoarthritis, dental focal infection, CRP, ESR. DOI: 10.18044/Medinform.201852.846