Indian Journal of Traditional Knowledge Vol. 17(4), October 2018, pp. 623-634 Exploring the relationship between the prevalence rate of obsessive-compulsive disorder (OCD), climatology and friendly environment Sima Mansoori¹, Elham Shafee², Mohsen Faizi³, Farhang Mozaffar 4 & Hamidreza Khankeh 5 * 1,3,4 School of Architecture and Environmental Design, Iran University of Science and Technology (I.U.S.T.), Tehran, Iran; ²Graduated of Architecture faculty of Payam Noor University (PNU), Tehran, Iran; 5 Research Center in Emergency and Disaster Health, University of Social Welfare and Rehabilitation, Sciences (USWR), Koudakyar St., Daneshjoo Blvd, Evin, Tehran 19857-13834, Iran; Department of Clinical Science and Education, Karolinska Institute, Södersjukhuset (KI SÖS), Sjukhusbacken 10, Stockholm 118 83, Sweden, Scientific Board Member of IPT E.V Leipzig, Germany E-mails: hamid.khankeh@ki.se; s_mansouri@cmps2.iust.ac.ir; Received 18 September 2017, revised 18 May 2018 The relationship between climatology and obsessive-compulsive disorder (OCD) has not been sufficently considered and the gaps have been left unfilled. This article aimed at finding the relationship between climatology and behavior setting in OCD patients. The current study is a descriptive relational study based on a literature review. Eleven databases from four related disciplines were searched, including interdisciplinary, health, Iranian Red Crescent Medical Journal (Ircmj) and Iranian medical university. Of the 1960 papers identified, 39 met the eligibility criteria and quality for selection from different geographic regions all over the world. Findings indicate different climatic conditions lead to variable OCD prevalence rate. The most frequent OCD patients are related in cold and dry climatic conditions. Also the lowest frequency OCD patients are related in hot and humid weather and climatology. There are clear relationship between climatology and OCD prevalence. And this is in line with the theory of Avicenna. To develop and elaborate the studies based on the friendly environment principle besides including the results of this investigation based on Avicenna theory. Further investigation is recommended to find the direction of relationship between two important factors. Keywords: Obsessive-compulsive disorder (OCD), Climatology, Criteria friendly environment IPC Int. Cl. 8 : A61B 5/00, A61P 11/04, A61P 15/02, A61P 15/12, A61P 15/14, G06Q 50/02, G06Q 10/06, G06Q 10/04, B29C 64/364, G01Q 30/10 There are some studies investigating the influences of environmental variables on mental health 1-3 . However, understanding of how the interaction between individual and environmental variables helps attaining to the broad perception of human experience needs more studies. According to World Health Organization (WHO), OCD has disturbed the progress of individual lives and social and family values 4-7 . The facts on OCD have been pointed out by Fontenelle & Hasler 8 , who reported the presence of a large difference among diverse countries in this regard. OCD is represented by diverse groups of symptoms, including intrusive thoughts, preoccupations, and internal compulsions. These recurrent obsessions or compulsions cause severe distress to a person 9,10 . The specific risk factors for the persistence of OCD include familial 11 , and genetic factors 12 , emotional neglect by parents 13 , and a prolonged labor and edema during pregnancy 14 and climatology 15 . Also The influences of climate change are predicted quality variation on environment 16,17 especially on environmental health. On the other hand the relationship between climate and health and similar practical problems may be addressed in an almost endless series in this field. In his interesting book entitled Anthropogeographie, Friedrich Ratzel presented more complete climatology by frequently referring to their effects on human health and activities. Also, climatology on mankind has been elaborated by Dr. Ellsworth Huntington in his article conclusion, he drew attentions to their impacts on human health and his physical and mental —————— *Corresponding author