Journal of Pharmaceutical Negative Results ¦ Volume 13 ¦ Special Issue ¦ 2022 1890 “A study to assess the knowledge regarding warning signs of cancer among home-maker women in the selected areas of Pune city” Vinita Jamdade 1 , Jadhav Sonali 2 , Jagatap Suchita 3 , Momin Akib 4 , Shere Ravi 5 1 Clinical Instructor Bvcon, Pune 2,3,4,5 GNM nursing students, Bharati Vidyapeeth School Of Nursing, Pune DOI: 10.47750/pnr.2022.13.S08.228 Introduction: When aberrant cells proliferate uncontrolled, cross their normal borders to infiltrate other body parts and/or move to other organs, the result is cancer, a broad category of disorders that may begin in almost any function or muscle. The latter phase, known as metastasizing, is a significant contributor to cancer-related mortality. Other synonyms for cancer include neoplasm and malignant tumour. Approximately 9.6 million fatalities, or one in every six deaths, were attributed to cancer in 2018, making it the second largest cause of death worldwide. Methodology: In the present study Descriptive Survey research design was used. Data collected on 500 samples. Tool was constructed to identify the demographic variables, and a set of self-structured questionnaires on knowledge regarding warning signs of cancer in home- maker women. Result: The main results about the degree of awareness of cancer warning signals among Home-Maker women are that 497 (99.4%) of the women have average knowledge, 3 (0.6%) have poor knowledge, and 0 (0%), have high knowledge. The mean awareness of cancer warning signals amongst Home-Maker women is 9.37, with a standard deviation of 0.74. Conclusion: The research was carried out to see how well Home-Maker women in certain parts of Pune city were informed about cancer warning indicators. The analysis was conducted to evaluate Home-Maker women’s awareness of cancer warning indicators. It demonstrates the average knowledge score of most married women. The level of understanding and their demographics did not significantly correlate with one another. Recommendation: A similar study can be done on urban population. Keywords: Assess, Knowledge, Warning signs, Cancer, Home- maker. INTRODUCTION When aberrant cells proliferate uncontrolled, cross their normal borders to infiltrate other body parts and/or move to other organs, the result is cancer, a broad category of disorders that may begin in almost any function or muscle. The latter phase, known as metastasizing, is a significant contributor to cancer-related mortality. Other synonyms for cancer include neoplasm and malignant tumor. Approximately 9.6 million fatalities, or one in every six deaths, were attributed to cancer in 2018, making it the second largest cause of death worldwide. Compared to women, who are more likely to acquire breast, colorectal, lung, cervical, and thyroid cancer, males are more likely to develop lung, prostate, colorectal, stomach, and liver cancer. The burden of cancer continues to rise globally, putting great physical, mental, and financial strain on individuals, families, communities, and health systems. Numerous health institutions in low- and middle-income countries are least prepared to manage this burden, leaving a large proportion of cancer patients without access to quick, high-quality diagnosis and treatment. The availability of early identification, high-quality treatment, and survivorship care in nations with robust health systems has improved the survival rates of several cancer forms. With a projected 570 000 new cases in 2018, which accounted for 7.5% of all female global disease burden, cancer - related deaths most common malignancy in women. More than 85% of the projected 311 000 deaths from uterine cancer each year take place in less developed areas. In affluent nations, there are programmer in place that allow women to undergo routine screenings and girls to get the HPV vaccine. A malignancy may spread to surrounding organs, blood vessels, or nerves or start to press on them. Some of the symptoms and indications of cancer are brought on by this pressure