Inborn Errors of Immunity in Algerian Children and Adults: A Single-Center Experience Over a Period of 13 Years (2008–2021) Brahim Belaid 1 , Lydia Lamara Mahammed 1 , Ouardia Drali 2 , Aida Mohand Oussaid 3 , Nabila Souad Touri 4 , Souhila Melzi 5 , Abdelhak Dehimi 6 , Lylia Meriem Berkani 1 , Fatma Merah 7 , Zineb Larab 7 , Ines Allam 1 , Ouarda Khemici 8 , Sonya Yasmine Kirane 9 , Mounia Boutaba 10 , Reda Belbouab 11 , Hadjira Bekkakcha 10 , Assia Guedouar 10 , Abdelhakim Chelali 12 , Brahim Baamara 12 , Djamila Noui 13 , Hadda Baaziz 13 , Radia Rezak 14 , Sidi Mohamed Azzouz 15 , Malika Aichaoui 16 , Assia Moktefi 16 , Redha Mohamed Benhatchi 16 , Meriem Oussalah 17 , Naila Benaissa 18 , Amel Laredj 18 , Assia Bouchetara 18 , Abdelkader Adria 19 , Brahim Habireche 20 , Noureddine Tounsi 20 , Fella Dahmoun 21 , Rabah Touati 21 , Hamza Boucenna 3 , Fadila Bouferoua 3 , Lynda Sekfali 3 , Nadjet Bouhafs 5 , Rawda Aboura 5 , Sakina Kherra 10 , Yacine Inouri 22 , Saadeddine Dib 23 , Nawel Medouri 24 , Noureddine Khelfaoui 24 , Aicha Redjedal 24 , Amara Zelaci 25 , Samah Yahiaoui 26 , Sihem Medjadj 27 , Tahar Khelifi Touhami 28 , Ahmed Kadi 29 , Fouzia Amireche 30 , Imane Frada 31 , Shahrazed Houasnia 32 , Karima Benarab 33 , Chahynez Boubidi 10 , Yacine Ferhani 11 , Hayet Benalioua 11 , Samia Sokhal 11 , Nadia Benamar 34 , Samira Aggoune 35 , Karima Hadji 36 , Asma Bellouti 37 , Hakim Rahmoune 6 , Nada Boutrid 6 , kamelia Okka 6 , Assia Ammour 38 , Houssem Saadoune 39 , Malika Amroun 22 , Hayet Belhadj 22 , Amina Ghanem 40 , Hanane Abbaz 40 , Sana Boudrioua 41 , Besma Zebiche 42 , Assia Ayad 42 , Zahra Hamadache 42 , Nassima Ouaras 43 , Nassima Achour 43 , Nadira Bouchair 44 , Houda Boudiaf 45 , Dahila Bekkat-Berkani 46 , Hachemi Maouche 35 , Zahir Bouzrar 5 , Lynda Aissat 47 , Ouardia Ibsaine 48 , Belkacem Bioud 6 , Leila Kedji 4 , Djazia Dahlouk 22 , Manoubia Bensmina 49 , Abdelkarim Radoui 17 , Mimouna Bessahraoui 15 , Nadia Bensaadi 33 , Azzeddine Mekki 2 , Zoulikha Zeroual 10 , Koon-Wing Chan 50 , Daniel Leung 50 , Amar Tebaibia 51 , Soraya Ayoub 52 , Dalila Mekideche 53 , Merzak Gharnaout 29 , Jean Laurent Casanova 54,55,56,57 , Anne Puel 54,55,56 , Yu Lung Lau 50 , Nacira Cherif 9 , Samir Ladj 58 , Leila Smati 46 , Rachida Boukari 11 , Nafissa Benhalla 3 and Reda Djidjik 1 * 1 Department of Medical Immunology, Beni Messous University Hospital Center, University of Algiers 1, Algiers, Algeria, 2 Department of Pediatrics B, Hussein Dey University Hospital Center, University of Algiers 1, Algiers, Algeria, 3 Department of Pediatrics A, Beni Messous University Hospital Center, University of Algiers 1, Algiers, Algeria, 4 Department of Pediatrics, Blida University Hospital Center, University of Blida, Blida, Algeria, 5 Department of Pediatrics, Bab El Oued University Hospital Center, University of Algiers 1, Algiers, Algeria, 6 Department of Pediatrics, Setif University Hospital Center, University of Setif 1, Setif, Algeria, 7 Department of Medical Immunology, Beni Messous University Hospital Center, Algiers, Algeria, 8 Department of Pediatrics B, Beni Messous University Hospital Center, Algiers, Algeria, 9 Department of Pediatrics B, Beni Messous University Hospital Center, University of Algiers 1, Algiers, Algeria, 10 Department of Pediatrics A, Hussein Dey University Hospital Center, University of Algiers 1, Algiers, Algeria, 11 Department of Pediatrics, Mustapha Pacha University Hospital Center, University of Algiers 1, Algiers, Algeria, 12 Department of Pediatrics, Djelfa Public Hospital Institution, Djelfa, Algeria, 13 Department of Pediatrics, Batna University Hospital center, University of Batna, Batna, Algeria, 14 Department of Pediatric Gastroenterology and Nutrition, Canastel Children’s Hospital, Oran, Algeria, 15 Department of Pediatric Gastroenterology and Nutrition, Canastel Children’s Hospital, University of Oran, Oran, Algeria, 16 Department of Pediatric Pneumo-Allergology, Canastel Children’s Hospital, Oran, Algeria, 17 Department of Pediatric Pneumo-Allergology, Canastel Children’s Hospital, University of Oran, Oran, Algeria, 18 Department of Children’s Infectious Diseases, Canastel Children’s Hospital, University of Oran, Oran, Algeria, 19 Department of Pediatric Hematology, Canastel Children’s Hospital, Frontiers in Immunology | www.frontiersin.org April 2022 | Volume 13 | Article 900091 1 Edited by: Waleed Al-Herz, Kuwait University, Kuwait Reviewed by: Kathleen Sullivan, Children’s Hospital of Philadelphia, United States Javier Chinen, Baylor College of Medicine, United States *Correspondence: Reda Djidjik ourtilane@yahoo.fr Specialty section: This article was submitted to Primary Immunodeficiencies, a section of the journal Frontiers in Immunology Received: 19 March 2022 Accepted: 25 March 2022 Published: 21 April 2022 ORIGINAL RESEARCH published: 21 April 2022 doi: 10.3389/fimmu.2022.900091