265.6
The Posterior Tibial Artery Flap as a Sentinel Flap in Face
Transplant: Maximizing Solid Organ and Composite Tissue
Allotransplant Team Coordination
Hatem Amer
2
, Marissa Suchyta
1
, Brian Carlsen
1
, Karim Bakri
1
,
Samir Mardini
1
1
Plastic Surgery, Mayo Clinic, Rochester, MN, United States;
2
Nephrology, Mayo Clinic, Rochester, MN, United States.
Facial vascularized composite tissue procurement has unique logistical
challenges and requires immense coordination with the solid organ pro-
curement teams.
[1]
One aspect of the procedure is the procurement of a
sentinel flap. Sentinel flaps are utilized in some centers for remote-site re-
jection monitoring in facial vascularized composite tissue allotransplanta-
tion, thus minimizing biopsies of the facial graft. Routine biopsies are
performed on the sentinel flap and the facial allograft is biopsied only
when the histopathology of the graft demonstrates a Grade I rejection
or higher.
[2]
Harvesting the sentinel flap is an added challenge, especially
since it is ideal to harvest prior to aorta cross-clamp to minimize ischemia
time and prevent thrombus. Reported flaps used as sentinel flaps are the
radial forearm flap, which have generally been inset into the groin of the
recipient.
[3]
However, the radial forearm flap harvest places the procuring
surgeon in the midst of the solid organ procurement teams, thus poten-
tially complicating solid organ harvesting. We present our experience
with the use of the posterior tibial artery flap as a sentinel flap in facial
vascularized composite tissue allotransplantation. This flap is an ideal
donor sentinel flap due to its location far from both the face transplant
and solid organ procurement teams, its reliable vascular pedicle, and
its ease of harvest.
[4]
We demonstrate the first utilization of this flap and
believe that the use of this flap could maximize the ability for solid organ
transplant teams to simultaneously perform solid organ harvesting while
the sentinel flap is being raised, thus enabling a more streamlined pro-
cess and better coordination in composite tissue allotransplantation.
References:
1. Chim H, Amer H, Mardini S, Moran SL. Vascularized composite allo-
transplant in the realm of regenerative plastic surgery. Mayo Clinic Proceed-
ings; 2014: Elsevier; 2014. p. 1009-20.
2. Sis B, Mengel M, Haas M, et al. Banff ’09 meeting report: antibody
mediated graft deterioration and implementation of Banff working groups.
American journal of transplantation. 2010;10(3):464-71.
3. Kueckelhaus M, Fischer S, Lian CG, et al. Utility of sentinel flaps in
assessing facial allograft rejection. Plastic and reconstructive surgery. 2015;
135(1):250-8.
4. Mardini S, Salgado CJ, Chen H-C, Yazar S, Ozkan O, Sassu P. Posterior
tibial artery flap in poliomyelitis patients with lower extremity paralysis. Plastic
and reconstructive surgery. 2006;117(2):640-5.
315.1
International Initiative to Enhance the Organ Donation and
Transplantation Systems in the Black Sea Area: The BSA Project
Estephan Arredondo
1
, Marta López-Fraga
2
, Marie-Odile Ott
2
,
Karl-Heinz Buchheit
2
, Karim Laoubdia
3
, Pavla Brezoysky
4
,
Alessandro Nanni Costa
5
, Efstratios Chatzixiros
5
, Ana França
6
,
Beatriz Dominguez
7
, Maria Paula Gómez
1
, Chloë Ballesté
1
,
Martí Manyalich
1
1
DTI Foundation, Barcelona, Spain;
2
European Directorate for the
Quality of Medicines & HealthCare (EDQM), Council of Europe,
Strasbourg, France;
3
Agence de la Biomédecine-ABM, Saint-Denis,
France;
4
Koordinační Středisko Transplantací, Prague, Czech Republic;
5
Centro Nazionale Trapianti-CNT, Roma, Italy;
6
Autoridade para os
Serviços de Sangue e da Transplantaçao- ASST, Lisboa, Portugal;
7
Organización Nacional de Trasplantes, Madrid, Spain.
Background: The Council of Europe (CoE) launched in 2011 a three-year
collaboration project that aimed to battle organ shortage and improve the ac-
cess to transplant health services in the Council of Europe BSA member
states (Armenia, Azerbaijan, Bulgaria, Georgia, Moldova, Rumania, Russian
Federation, Turkey and Ukraine) through the development of safe and ethical
Donation and Transplantation (D&T) programmes.
Objective: To support the development of D&T programmes through close
inter-state cooperation between national health organisations and relevant
stakeholders.
Methodology: Focused in the level of development of D&T in each Black
Sea Area (BSA) member state, the following working packages (WP) were
established: a) WP1: Coordination of the Project (CoE), b)WP2: Development
and implementation of an effective legislative and financial framework (Czech
Republic and France), c)WP3: Establishment of National Transplant Authori-
ties (Italy and Portugal), d)W4 Clinical Practices (Spain and DTI Foundation).
Data collection, surveys and experts visits were performed to get first-
hand information in each participant country at national, regional and hospital
level by detecting problems and proposing solutions.
Results: Data analysis showed a positive impact of the project repre-
sented by a tendency to raise the D&Trates in all the countries. (Azerbaijan
raised 7,3%, Armenia decreased 0.7%, Georgia Raised 3,3%, Bulgaria
raised 0,9%, Moldova raised 2,5%, Ukraina raised 0,8% and Turkey raised
1,6%) Figure 1.
In addition, the Project recommendations have been assimilated in the
strategic plans of the participant countries.
Conclusions: The increase of the donation rates is a result of an imple-
mentation of legislative, organizational and institutional recommendations
performed by the CoE, the efforts of the Ministry of Health (MOH) of each
country and synergies with other European projects placed in the BSA area.
BSA project made possible to analyse, assess and compare the different
legal and organizational systems of the BSA countries. As a consequence of
the outcomes, BSA countries should invest themselves in the implemen-
tation of the recommendations resulting from this project in order to achieve
their organ donation and transplantation system self-sufficiency.
FIGURE 1.
S50 Transplantation
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August 2017
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Volume 101
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Number 8S-2 www.transplantjournal.com
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